135080-81-8

Basic information

• Product Name: {(2S,5R)-5-[3-(4-Methoxy-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-2,5-dihydro-furan-2-ylmethoxymethyl}-phosphonic acid diethyl ester
• Synonyms: {(2S,5R)-5-[3-(4-Methoxy-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-2,5-dihydro-furan-2-ylmethoxymethyl}-phosphonic acid diethyl ester
• CAS NO: 135080-81-8
• Molecular Weight: 480.455
• Mol File: 135080-81-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(2S,5R)-5-[3-(4-Methoxy-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-2,5-dihydro-furan-2-ylmethoxymethyl}-phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(2S,5R)-5-[3-(4-Methoxy-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-2,5-dihydro-furan-2-ylmethoxymethyl}-phosphonic acid diethyl ester(135080-81-8)
• EPA Substance Registry System: {(2S,5R)-5-[3-(4-Methoxy-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-2,5-dihydro-furan-2-ylmethoxymethyl}-phosphonic acid diethyl ester(135080-81-8)

Safety Data

• Hazardous Substances Data: 135080-81-8(Hazardous Substances Data)

Upstream product

• 42867-74-3 1-(5-O-acetyl-2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)-uracil 
• 5974-93-6 2',3'-dideoxy-2',3'-didehydrouridine 
• 31618-90-3 diethyl (p-toluenesulfonyloxymethane)phosphonate 
• 135080-80-7 1-((2R,5S)-5-Hydroxymethyl-2,5-dihydro-furan-2-yl)-3-(4-methoxy-benzyl)-1H-pyrimidine-2,4-dione 

Downstream Products

• 135080-82-9 {(2S,5R)-5-[3-(4-Methoxy-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-2,5-dihydro-furan-2-ylmethoxymethyl}-phosphonic acid 

Relevant articles and documents

SYNTHESIS OF 5'-O-PHOSPHONOMETHYL-2',3'-DIDEHYDRO-2',3'-DIDEOXYURIDINE BY USE OF P-METHOXYBENZYL AS A N3-PROTECTING GROUP.

Uridine derivatives are protected at N3-position with a p-methoxybenzyl group under Mitsunobu conditions.Selective removal is possible with ceric ammonium nitrate.The otherwise difficult to obtain 5'-O-phosphonomethyl d4U was prepared using thi