135082-47-2

Upstream product

• 135082-46-1 6-(benzyloxy)-10-methyl-1,2,3,4,5-pentamethoxyacridin-9-one 
• 135082-42-7 4-(benzyloxy)-3-methoxy-N-(2,3,4,5-tetramethoxyphenyl)anthranilic acid 
• 135082-45-0 6-(benzyloxy)-1,2,3,4,5-pentamethoxyacridin-9-one 
• 23938-73-0 2-amino-3-methoxy-4-benzyloxybenzoic acid 
• 3584-32-5 4-(benzyloxy)-3-methoxy-2-nitrobenzoic acid 

Downstream Products

• 82354-35-6 des-N-methylnoracronycine 

Relevant academic research and scientific papers

Synthesis of the acridone alkaloids glyfoline and congeners. Structure- activity relationship studies of cytotoxic acridones

Glyfoline (4, 1,6-dihydroxy-10-methyl-2,3,4,5-tetramethoxyacridin-9-one) and its congeners were synthesized for evaluation of their cytotoxicity. A detailed structure-activity relationships (SAR) of these acridone derivatives were also studied. To study t

SYNTHESIS OF GLYFOLINE, A CONSTITUENT OF GLYCOSMIS CITRIFOLIA (WILLD.) LINDL. AND A POTENTIAL ANTICANCER AGENT

Condensation of 4-benzyloxy-3-methoxyanthranilic acid (3) with 5-iodo-1,2,3,4-tetramethoxybenzene (4) gave 6-benzyloxy-1,2,3,4,5-pentamethoxy-9-acridone (7), which was then converted into glyfoline (1) via N-methylation, selective de-O-methylation, and de