1350820-23-3

Basic information

• Product Name: (R)-3-(4-chlorophenyl)-3-hydroxy-1-[(S)-5-isopropyl-3-phenyl-2-thioxoimidazolidin-1-yl]propan-1-one
• Synonyms: (R)-3-(4-chlorophenyl)-3-hydroxy-1-[(S)-5-isopropyl-3-phenyl-2-thioxoimidazolidin-1-yl]propan-1-one
• CAS NO: 1350820-23-3
• Molecular Weight: 402.945
• Mol File: 1350820-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-(4-chlorophenyl)-3-hydroxy-1-[(S)-5-isopropyl-3-phenyl-2-thioxoimidazolidin-1-yl]propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-(4-chlorophenyl)-3-hydroxy-1-[(S)-5-isopropyl-3-phenyl-2-thioxoimidazolidin-1-yl]propan-1-one(1350820-23-3)
• EPA Substance Registry System: (R)-3-(4-chlorophenyl)-3-hydroxy-1-[(S)-5-isopropyl-3-phenyl-2-thioxoimidazolidin-1-yl]propan-1-one(1350820-23-3)

Safety Data

• Hazardous Substances Data: 1350820-23-3(Hazardous Substances Data)

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 29635-81-2 (S)-5-isopropyl-3-phenyl-2-thioxoimidazolidin-4-one 
• 72-18-4 L-valine 
• 433285-46-2 (S)-4-isopropyl-1-phenylimidazolidin-2-thione 
• 1350820-11-9 (S)-N-acetyl-4-isopropyl-1-phenylimidazolidin-2-thione 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 1375081-89-2 (R)-baclofen hydrochloride 
• 123632-35-9 (R)-(-)-4-(4-chlorophenyl)pyrrolidin-2-one 
• 537676-65-6 ethyl (3S)-3-bromo-3-(4-chlorophenyl)propanoate 
• 537676-63-4 ethyl (3R)-3-cyano-3-(4-chlorophenyl)propanoate 
• 141545-22-4 (R)-3-hydroxy-3-(4-chlorophenyl)-propionic acid ethyl ester 

Relevant articles and documents

Asymmetric induction by (S)-4-isopropyl-1-phenylimidazolidin-2-thione in titanium-mediated aldol reactions and its application in enantioselective synthesis of (R)-baclofen

The usefulness of (S)-4-isopropyl-1-phenylimidazolidin-2-thione as a chiral auxiliary in stereoselective propionate and acetate aldol reactions is discussed. Further, the enantioselective synthesis of (R)-baclofen by acetate aldol reaction using the chiral auxiliary was demonstrated. Georg Thieme Verlag Stuttgart New York.