135085-60-8Relevant academic research and scientific papers
Metalation of diazines IV. Lithiation of sym-disubstituted pyrazines
Turck, A.,Trohay, D.,Mojovic, L.,Ple, N.,Queguiner, G
, p. 301 - 310 (2007/10/02)
Conditions for the metalation of 2,6-dichloro- and 2-6-dimethoxy-pyrazine are defined and the lithio-derivatives are shown to react with some electrophiles.A convenient synthesis of a diazaxanthone from the lithio-derivative of the dichloro-compund is des
The Convergent Synthesis of Pyrazinyl and Quinoxalinyl Phenylmethanones from 2-Lithio Pyrazines and Quinoxalines
Ward, John S.,Merritt, Leander
, p. 765 - 768 (2007/10/02)
Pyrazines and quinoxalines bearing 2-substituents that direct ortho metalation reacted with lithium 2,2,6,6-tetramethylpiperidide to produce 2-substituted-3-lithiopyrazines and quinoxalines.These lithio reagents reacted with N-methoxy-N-methylbenzamide to
