4774-15-6

Basic information

• Product Name: 2,6-Dimethoxypyrazine
• Synonyms: 2,6-dimethoxypirazine;2,6-DIMETHOXYPYRAZINE;2,6-DIMETHOXYPYRAZINE,99+%
• CAS NO: 4774-15-6
• Molecular Formula: C₆H₈N₂O₂
• Molecular Weight: 140.14
• Product Categories: Pyrazines;Pyrazine
• Mol File: 4774-15-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 31-31.5 °C
• Boiling Point: 184.849 °C at 760 mmHg
• Flash Point: 65.718 °C
• Appearance: /
• Density: 1.131
• Vapor Pressure: 0.984mmHg at 25°C
• Refractive Index: 1.49
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 0.15±0.10(Predicted)
• CAS DataBase Reference: 2,6-Dimethoxypyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethoxypyrazine(4774-15-6)
• EPA Substance Registry System: 2,6-Dimethoxypyrazine(4774-15-6)

Safety Data

• Hazardous Substances Data: 4774-15-6(Hazardous Substances Data)

Usage

General Description

2,6-Dimethoxypyrazine is a naturally occurring organic compound belonging to the chemical class of pyrazines, which are heterocyclic aromatic compounds. It's characterized by its earthy, vegetal aroma and is commonly found in wines, certain fruits and vegetables, as well as other foods and beverages. 2,6-Dimethoxypyrazine contributes to the flavor profile of these edibles and plays a notable role in the wine industry, where it's associated with the 'green', 'grassy' or 'herbaceous' notes in wines, particularly those produced in the Bordeaux region. 2,6-Dimethoxypyrazine can also be produced synthetically for use as a flavouring agent.

InChI:InChI=1/C6H8N2O2/c1-9-5-3-7-4-6(8-5)10-2/h3-4H,1-2H3

Upstream product

• 4774-14-5 2,6-dichloropyrazine 
• 124-41-4 sodium methylate 
• 23229-25-6 2,6-dibromopyrazine 

Downstream Products

• 181582-02-5 (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-2-(3,5-dimethoxy-pyrazin-2-yl)-tetrahydro-furan-2-ol 
• 23229-25-6 2,6-dibromopyrazine 
• 136866-42-7 (2,6-dimethoxy-3-pyrazinyl)-2'-methoxyphenyl methanone 
• 136866-48-3 2,6-dimethoxy-3-phenylethynylpyrazine 
• 181581-97-5 2-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3,5-dimethoxy-pyrazine 
• 135085-60-8 (2,6-dimethoxy-3-pyrazinyl)phenylmethanone 
• 136866-38-1 2,6-dimethoxy-3-pyrazinecarboxaldehyde 
• 136866-37-0 (2,6-dimethoxy-3-pyrazinyl)-2'-methoxyphenyl methanol 

Relevant articles and documents

Synthesis of 7-Azidofurazano[3,4-b]tetrazolopyrazine and isomer's structure in different polarity solvents

7-Azidofurazano[3,4-b]tetrazolopyrazine (FSZPA) was synthesized via methoxylation, nitration hydrazinolysis and azidation, using 2,6- dichloropyrazine as a starting material. The structures of 7-azidofurazano[3,4- b]tetrazolopyrazine and intermediates were identified by FTIR, NMR and elemental analysis. 15N and 13C NMR spectra showed three isomer forms resulting from the reversible opening and closing between asido and tetrazole depending on polarity of the solvents.

A method for synthesizing dibromo compounds

The present invention belongs to the field of synthesis technology of compounds, specifically disclosed a method of synthesis of dibromo compounds. The method of the present invention takes a dichloro compound as a raw material, first reacts with sodium methanol to form a dimethoxy compound, and then reacts with a bromination reagent to give a dibromo compound. The method of the present invention is not only mild reaction conditions, simple operation, and the reaction product is single, through simple post-treatment, and then the target product can be obtained at a high yield, it is expected to be developed as an industrial production method.

Synthetic method for 2,6-diamino-3,5-dinitro-1-oxypyrazine

The invention relates to a synthetic method for a compound, especially to a synthetic method for 2,6-diamino-3,5-dinitro-1-oxypyrazine. The method comprises the following steps: subjecting sodium methoxide and dibromopyrazine to methylation; then carrying