1350852-16-2Relevant academic research and scientific papers
Stable triplex formation using the strong stacking effect of consecutive thionucleoside moieties
Ohkubo, Akihiro,Nishino, Yudai,Yokouchi, Akira,Ito, Yu,Noma, Yasuhiro,Kakishima, Yuuki,Masaki, Yoshiaki,Tsunoda, Hirosuke,Seio, Kohji,Sekine, Mitsuo
, p. 12556 - 12558 (2011)
In this study, it was found that the arrangement of consecutive thiocarbonyl groups of s2T and m5s2C remarkably stabilized the pre-protonated form of the triplex, and that the stabilization of the pre-protonated form increased the pKa value of a cytosine derivative in the triplex.
