1350889-89-2

Upstream product

• 415726-81-7 (2R,3R,4S,6R)-2,3:4,5-bis(isopropylidenedioxy)-1-cyclohexanone 
• 488-73-3 (+)-proto-quercitol 
• 1350889-87-0 C₁₇H₁₈O₄ 
• 1350889-86-9 C₃₀H₂₆O₈ 
• 1157852-09-9 1,2:3,4-di-O-isopropylidene-5R-(+)-proto-quercitol 
• 532-32-1 sodium benzoate 
• 1350889-88-1 C₁₇H₁₈Br₂O₄ 

Downstream Products

• 442851-90-3 (1R,2S,3S,4S)-5-hydroxymethyl-1-octylamino-2,3,4-trihydroxycyclohex-5-ene 

Relevant academic research and scientific papers

Transformation of quercitols into 4-methylenecyclohex-5-ene-1,2,3-triol derivatives, precursors for the chemical chaperones N-octyl-4-epi-β- valienamine (NOEV) and N-octyl-β-valienamine (NOV)

(+)-proto-Quercitol (1) and (-)-vibo-quercitol (2), both of which could be readily prepared by the bioconversion of myo-inositol, were successfully converted into the corresponding 4-methylenecyclohex-5-ene-1,2,3-triol derivatives. These compounds were demonstrated to be suitable precursors, preserving their configurations, for bioactive carba-aminosugars such as the potent chemical chaperone drug candidates, N-octyl-4-epi-β-valienamine (NOEV, 3) and N-octyl-β-valienamine (NOV, 4).