135091-08-6

Upstream product

• 100-44-7 benzyl chloride 
• 135068-37-0 N-{3-[(2R,6S)-6-((1S,2R)-1,2-Bis-benzyloxy-heptyl)-2-(2,2-dimethoxy-ethyl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-N-[4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-4-methyl-benzenesulfonamide 
• 135068-34-7 [(2S,6S)-6-((1S,2R)-1,2-Bis-benzyloxy-heptyl)-1-(3-{(toluene-4-sulfonyl)-[4-(2,2,2-trifluoro-acetylamino)-butyl]-amino}-propyl)-1,2,3,6-tetrahydro-pyridin-2-yl]-acetic acid methyl ester 
• 135068-33-6 N-{4-[{3-[(2R,6S)-6-((1S,2R)-1,2-Bis-benzyloxy-heptyl)-2-(2,2-dimethoxy-ethyl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-(toluene-4-sulfonyl)-amino]-butyl}-2,2,2-trifluoro-acetamide 
• 135068-61-0 N-{3-[(2R,6S)-6-((1S,2R)-1,2-Bis-benzyloxy-heptyl)-2-(2,2-dimethoxy-ethyl)-3,6-dihydro-2H-pyridin-1-yl]-3-oxo-propyl}-4-methyl-benzenesulfonamide 
• 135068-32-5 N-{3-[(2R,6S)-6-((1S,2R)-1,2-Bis-benzyloxy-heptyl)-2-(2,2-dimethoxy-ethyl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-4-methyl-benzenesulfonamide 
• 135068-30-3 (2R,6S)-6-((1S,2R)-1,2-Bis-benzyloxy-heptyl)-1-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-pyridine-2-carboxylic acid butyl ester 
• 135068-31-4 (2R,6S)-6-((1S,2R)-1,2-Bis-benzyloxy-heptyl)-2-(2,2-dimethoxy-ethyl)-1-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-pyridine 
• 135068-36-9 (2R,6S)-6-((1S,2R)-1,2-Bis-benzyloxy-heptyl)-2-((E)-2-methoxy-vinyl)-1-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-pyridine 
• 135068-35-8 [(2R,6S)-6-((1S,2R)-1,2-Bis-benzyloxy-heptyl)-1-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-pyridin-2-yl]-methanol 
• 135068-60-9 (2R,6S)-6-((1S,2R)-1,2-Bis-benzyloxy-heptyl)-2-(2,2-dimethoxy-ethyl)-1,2,3,6-tetrahydro-pyridine 
• 135068-29-0 (E)-(4S,5R)-4,5-Bis-benzyloxy-dec-2-enoic acid ethyl ester 
• 135068-39-2 (E)-(4S,5R)-4,5-Bis-benzyloxy-dec-2-en-1-ol 
• 128038-15-3 C₂₅H₃₂O₂ 

Relevant academic research and scientific papers

A chiral synthesis of (-)-cannabisativine: An application of the highly diastereo-selective hetero Diels-Alder reaction

The polyamine alkaloid cannabisativine was synthesized as an optical active form. The key step is the hetero Diels-Alder reaction of chiral diene and an N-tosylimine, in which regio- and diastereo-face selectivities were completely controlled, only one diastereomer was isolated in high yield. Synthesized (-)-cannabisativine has the same physical data as the natural product except for the αD value.