1350928-27-6

Basic information

• Product Name: (E)-3-cinnamoyl-7-methoxy-2H-chromen-2-one
• Synonyms: (E)-3-cinnamoyl-7-methoxy-2H-chromen-2-one
• CAS NO: 1350928-27-6
• Molecular Weight: 306.318
• Mol File: 1350928-27-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-cinnamoyl-7-methoxy-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-cinnamoyl-7-methoxy-2H-chromen-2-one(1350928-27-6)
• EPA Substance Registry System: (E)-3-cinnamoyl-7-methoxy-2H-chromen-2-one(1350928-27-6)

Safety Data

• Hazardous Substances Data: 1350928-27-6(Hazardous Substances Data)

Upstream product

• 108-46-3 recorcinol 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 10441-27-7 3-acetyl-7-hydroxy-chromen-2-one 

Downstream Products

• 1350928-29-8 C₂₁H₂₀O₅S 

Relevant articles and documents

The development of a fluorescence turn-on sensor for cysteine, glutathione and other biothiols. A kinetic study

Two fluorescence probes for the detection of cysteine (Cys), glutathione (GSH) and other biothiols, such as homocysteine (Hcy) and cysteinyl-glycine (Cys-Gly), were developed. These molecular probes are coumarin-based derivatives containing a chalcone-like moiety that reacts with biothiols through a Michael addition reaction, leading to strong fluorescence enhancements. The reactivity of the tested biothiols toward both probes (ChC1 and ChC2) follows the order Cys > GSH > Hcy > Cys-Gly, ChC1 being less reactive than ChC2. Possible interference with other amino acids was assessed. ChC1 and ChC2 display a highly selective fluorescence enhancement with thiols, allowing these probes to be used for fluorimetric thiol determination in SH-SY5Y cells.