135094-11-0

Basic information

• Product Name: endo-2-aza-2-<(R)-1-phenylethyl>-3-ethoxycarbonyl<2.2.2>bicyclooct-5-ene
• CAS NO: 135094-11-0
• Molecular Weight: 285.386
• Mol File: 135094-11-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: endo-2-aza-2-<(R)-1-phenylethyl>-3-ethoxycarbonyl<2.2.2>bicyclooct-5-ene(CAS DataBase Reference)
• NIST Chemistry Reference: endo-2-aza-2-<(R)-1-phenylethyl>-3-ethoxycarbonyl<2.2.2>bicyclooct-5-ene(135094-11-0)
• EPA Substance Registry System: endo-2-aza-2-<(R)-1-phenylethyl>-3-ethoxycarbonyl<2.2.2>bicyclooct-5-ene(135094-11-0)

Safety Data

• Hazardous Substances Data: 135094-11-0(Hazardous Substances Data)

Upstream product

• 37662-05-8 ((R)-1-phenyl-ethylimino)-acetic acid ethyl ester 
• 1165952-91-9 cyclohexa-1,3-diene 

Relevant articles and documents

Bridged bicyclic vasopressin receptor antagonists with V2-selective or dual V1a/V2 activity

The synthesis and biological testing of a novel series of nonpeptide vasopressin receptor antagonists, containing a bridged bicyclic nucleus, are reported. Variation of substituents (R1-R3) in general formula 3, and the configuration

Enantio- and Diastereo-selective Synthesis of Pipecolic Acid Derivatives using the Aza-Diels-Alder Reaction of Imines with Dienes

Optically active pipecolic acid derivatives can be prepared by the aza-Diels-Alder reaction of simple dienes with the imine derived from ethyl glyoxylate and chiral 1-phenylethylamine; the cycloadditions are regiospecific, highly diastereoselective within the heterocyclic ring (>92percent exo with cyclic dienes, and 100percent endo with acyclic dienes), and lead to high asymmetric induction in most cases (average d.e. = 72percent).