37662-05-8

Basic information

• Product Name: Acetic acid, 2-[[(1R)-1-phenylethyl]iMino]-, ethyl ester
• Synonyms: Acetic acid, 2-[[(1R)-1-phenylethyl]iMino]-, ethyl ester;Ethyl D-(α-MethylbenzyliMino)acetate
• CAS NO: 37662-05-8
• Molecular Formula: C₁₂H₁₅NO₂
• Molecular Weight: 205.253
• Mol File: 37662-05-8.mol
• Article Data: 31

Chemical Properties

• Appearance: /
• Solubility: DCM
• CAS DataBase Reference: Acetic acid, 2-[[(1R)-1-phenylethyl]iMino]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, 2-[[(1R)-1-phenylethyl]iMino]-, ethyl ester(37662-05-8)
• EPA Substance Registry System: Acetic acid, 2-[[(1R)-1-phenylethyl]iMino]-, ethyl ester(37662-05-8)

Safety Data

• Hazardous Substances Data: 37662-05-8(Hazardous Substances Data)

Usage

Uses

Ethyl D-(α-Methylbenzylimino)acetate is an intermediate in the preparation of Argatroban (A769000).

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 64805-08-9 ethyl glyoxylate hydrate 
• 924-44-7 glyoxylic acid ethyl ester 

Downstream Products

• 139405-46-2 (2R,6R)-1-<(R)-1-phenylethyl>-6-ethoxycarbonyl-2-methyl-3,4-didehydropiperidine 
• 134984-67-1 (2S,6S)-1-<(R)-1-phenylethyl>-6-ethoxycarbonyl-2-methyl-3,4-didehydropiperidine 
• 135635-58-4 Ethyl (1R,3R,4S)-2-<(1R)-α-Phenylethyl>-2-azabicyclo<2.2.1>hept-5-ene-3-carboxylate 
• 134984-64-8 exo-2-aza-2-<(R)-1-phenylethyl>-3-ethoxycarbonyl<2.2.2>bicyclooct-5-ene 
• 169888-73-7 (1R,3S,4S)-2-<(R)-1-phenylethyl>-2-azabicyclo<2.2.1>heptane-3-exo-diphenylmethanol 
• 764622-98-2 (1S,3S,4R)-2-Aza-bicyclo[2.2.1]hept-5-ene-3-carboxylic acid ethyl ester 
• 134984-63-7 (1S,3S,4R)-2-((R)-1-phenyl-ethyl)-2-aza-bicyclo[2.2.1]hept-5-ene-3-carboxylic acid ethyl ester 
• 135094-10-9 endo-2-aza-2-<(R)-1-phenylethyl>-3-ethoxycarbonyl<2.2.1>bicyclohept-5-ene 
• 192461-70-4 ethyl (1R,3S,4S)-2-<(R)-1-phenylethyl>-2-azabicyclo<2.2.1>heptane-3-exo-carboxylate 
• 134984-62-6 (2R,4S)-4-Methyl-1-((R)-1-phenyl-ethyl)-piperidine-2-carboxylic acid ethyl ester 
• 134984-62-6 (2R,4R)-4-Methyl-1-((R)-1-phenyl-ethyl)-piperidine-2-carboxylic acid ethyl ester 
• 134984-77-3 ethyl trans-(2S,4R)-1-<(R)-1-phenylethyl>-4-methylpipecolate 
• 134984-62-6 ethyl cis-(2S,4R)-1-<(R)-1-phenylethyl>-4-methylpipecolate 
• 134984-65-9 (6S)-1-<(R)-1-phenylethyl>-6-ethoxycarbonyl-3,4-dimethyl-3,4-didehydropiperidine 

Relevant articles and documents

RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF

The present invention discloses a receptor inhibitor of formula (I), a pharmaceutical composition comprising the same and the use thereof.

ALKYNE COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS

Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula I, or a pharmaceutically acceptable salt or composition thereof wherein R12 or R13 on the A group is alkyne substituent (R32) are provided. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein can reduce the excessive activation of complement.

Substituted piperidine amide derivative, preparation method thereof, and application of derivative to pharmacy

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