135131-55-4Relevant academic research and scientific papers
The synthesis of oligodeoxynucleotides containing 4-thiothymidine residues
Nikiforov,Connolly
, p. 3851 - 3854 (1991)
Oligodeoxynucleotides containing 4-thiothymidine residues were obtained using the phosphoramidites of 2 and 3. Treatment with CH3COSK in EtOH was used to introduce the 4-thioketo function at the oligodeoxynucleotide level.
5′-O-(4-4′-dimethylthoxytrityl)-4-thiocyanatothymidine A useful intermediate for the preparation of various 4-substituted thymidine analogues
Nikiforov, Theo T.,Connolly, Bernard A.
, p. 2505 - 2508 (2007/10/02)
The thiocyanato group in 5′-O-(4,-4′-dimethoxytrityl)-4-thiocyanatothymidine 2 is easily displaced by a variety if O-, N=- and S-nucleophiles, making this compound a useful intermediate for the preparation of 4-substituted thymidine analogues.
