1351354-85-2Relevant academic research and scientific papers
The prins reaction using ketones: Rationalization and application toward the synthesis of the portentol skeleton
Jacolot, Maiwenn,Jean, Mickael,Levoin, Nicolas,Van De Weghe, Pierre
, p. 58 - 61 (2012/02/14)
We report a TMSI-promoted Prins cyclization reaction with ketones as carbonyl partners to prepare polysubstituted chiral spirotetrahydropyrans. In the presence of racemic 2-methylcyclohexanone a dynamic kinetic resolution occurred affording one stereoisom
