13515-12-3

Basic information

• Product Name: Benzoic acid, 2-(acetyloxy)-4-Methyl-, Methyl ester
• Synonyms: Benzoic acid, 2-(acetyloxy)-4-Methyl-, Methyl ester
• CAS NO: 13515-12-3
• Molecular Formula: C₁₁H₁₂O₄
• Molecular Weight: 208.21058
• Mol File: 13515-12-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 2-(acetyloxy)-4-Methyl-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(acetyloxy)-4-Methyl-, Methyl ester(13515-12-3)
• EPA Substance Registry System: Benzoic acid, 2-(acetyloxy)-4-Methyl-, Methyl ester(13515-12-3)

Safety Data

• Hazardous Substances Data: 13515-12-3(Hazardous Substances Data)

Upstream product

• 4670-56-8 methyl 2-hydroxy-4-methylbenzoate 
• 14504-07-5 2-acetoxy-4-methylbenzoic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 13339-10-1 methyl 2-acetoxy-4-(bromomethyl)benzoate 

Relevant articles and documents

Derivatives of 1,4-bis(3-hydroxycarbonyl-4-hydroxyl)styrylbenzene as PTP1B inhibitors with hypoglycemic activity

Disalicylic acid derivatives with stilbene and bis-styrylbenzene skeleton were synthesized as PTP1B inhibitors. The most potent in this series exhibited a submicromolar IC50 value. One of the compounds 7b was tested in an animal model for its efficacy as an anti-diabetic or an anti-obesity agent. In feeding compound 7b to diet-induced obese mice, no significant differences in weight gain and food consumption were observed between the drug-treated and the obese control mice. However, 7b significantly lowered the fasting glucose level and improved the glucose tolerance in the obesity-induced diabetic mice.

ORTHO SUBSTITUTED AROMATIC COMPOUNDS USEFUL AS ANTAGONISTS OF THE PAIN ENHANCING EFFECTS OF E-TYPE PROSTAGLANDINS

The invention relates to compounds of the formula (I): STR1 wherein A, B and D are various ring systems such as phenyl, R. sup.1 includes carboxy, R 3 is hydrogen or C 1-4 alkyl and Z is a linking group such as--(CH(R 5)) m--wherein m is 2, 3 or 4, and R 5 includes hydrogen and methyl; and pharmaceutically acceptable salts and in vivo hydrolysable esters or amides thereof, processes for preparing these compounds, pharmaceutical compositions comprising them, and their use in the treatment of pain.