1351800-58-2

Basic information

• Product Name: 2-(1,3-dioxolan-2-yl)-4,5-diethoxybenzonitrile
• Synonyms: 2-(1,3-dioxolan-2-yl)-4,5-diethoxybenzonitrile
• CAS NO: 1351800-58-2
• Molecular Weight: 263.293
• Mol File: 1351800-58-2.mol

Chemical Properties

• CAS DataBase Reference: 2-(1,3-dioxolan-2-yl)-4,5-diethoxybenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1,3-dioxolan-2-yl)-4,5-diethoxybenzonitrile(1351800-58-2)
• EPA Substance Registry System: 2-(1,3-dioxolan-2-yl)-4,5-diethoxybenzonitrile(1351800-58-2)

Safety Data

• Hazardous Substances Data: 1351800-58-2(Hazardous Substances Data)

Upstream product

• 139-85-5 3,4-dihydroxybenzaldehyde 
• 2029-94-9 3,4-diethoxybenzaldehyde 
• 91335-51-2 2-bromo-4,5-diethoxybenzaldehyde 
• 1351800-57-1 2-(2-bromo-4,5-diethoxyphenyl)-1,3-dioxolane 

Downstream Products

• 1351800-60-6 4,5-diethoxy-2-formylbenzonitrile 

Relevant articles and documents

Exquisite synthesis of a designed PAR-1 antagonist

The synthesis of a designed, sterically congested geminal dimethyl-bearing PAR-1 antagonist was achieved by a route of ten steps, with the oxidation of an electron-rich benzaldehyde, the construction of a tertiary alkyl azide, and the selective hydrogenolysis of a 1,5-fused tetrazole to generate the cyclic amidine with Raney-Ni being the key steps. The selective hydrogenolysis of 1,5-fused tetrazole to generate the cyclic amidine with Raney-Ni was discovered and may be generally used for the synthesis of structurally unusual cyclic amidines. Several unsuccessful attempts to construct the desired geminal dimethyl-bearing cyclic amidine were also discussed. Copyright