2029-94-9

Basic information

• Product Name: 3,4-DIETHOXYBENZALDEHYDE
• Synonyms: AKOS B000267;3,4-DIETHOXYBENZALDEHYDE;ASISCHEM R43189;OTAVA-BB BB7020401740;3,4-diethoxy-benzaldehyd;Benzaldehyde, 3,4-diethoxy-;3,4-DIETHOXYBENZALDEHYDE 98+%;3,4-DIETHOXYBENZALDE
• CAS NO: 2029-94-9
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• EINECS: 217-979-7
• Product Categories: Aromatic Aldehydes & Derivatives (substituted);BenzaldehydeDerivative;Aldehydes;C10 to C21;Carbonyl Compounds
• Mol File: 2029-94-9.mol
• Article Data: 14

Chemical Properties

• Melting Point: 22°C
• Boiling Point: 293-294 °C(lit.)
• Flash Point: 225 °F
• Appearance: pale yellow liquid
• Density: 1.097 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000862mmHg at 25°C
• Refractive Index: n20/D 1.5570(lit.)
• CAS DataBase Reference: 3,4-DIETHOXYBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIETHOXYBENZALDEHYDE(2029-94-9)
• EPA Substance Registry System: 3,4-DIETHOXYBENZALDEHYDE(2029-94-9)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 23-24/25
• WGK Germany: 2
• HazardClass: IRRITANT
• Hazardous Substances Data: 2029-94-9(Hazardous Substances Data)

Usage

General Description

3,4-Diethoxybenzaldehyde is an organic compound with the chemical formula C11H14O3. It is a colorless or light yellow liquid with a floral, sweet, and powdery odor. The compound is used in the pharmaceutical and fragrance industries as a building block for the synthesis of various compounds. It is also used in the creation of perfumes due to its pleasant odor. Additionally, 3,4-Diethoxybenzaldehyde has shown potential as an anti-inflammatory and analgesic agent in various studies, making it a promising candidate for further pharmaceutical development. However, it is important to use this chemical with caution due to its potential to cause skin and eye irritation.

InChI:InChI=1/C11H14O3/c1-3-13-10-6-5-9(8-12)7-11(10)14-4-2/h5-8H,3-4H2,1-2H3

Upstream product

• 74-96-4 ethyl bromide 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 64-67-5 diethyl sulfate 
• 2539-53-9 4-ethoxy-3-hydroxybenzaldehyde 
• 121-32-4 4-hydroxy-3-ethoxybenzaldehyde 
• 100-97-0 hexamethylenetetramine 
• 2050-46-6 1,2-diethoxybenzene 
• 120-80-9 benzene-1,2-diol 
• 75-03-6 ethyl iodide 
• 99272-94-3 2-ethoxy-4-(prop-1-en-1-yl)phenol 
• 63477-41-8 trans-2-ethoxy-5-(1-propenyl)-phenol 
• 68-12-2 N,N-dimethyl-formamide 
• 93-61-8 N-methyl-N-phenylformamide 
• 2029-95-0 1,2-diethoxy-4-trans-propenyl-benzene 

Downstream Products

• 92582-04-2 3-((Ξ)-3,4-diethoxy-benzylidene)-dihydro-furan-2-one 
• 97016-66-5 (3,4-diethoxy-benzyl)-(5-piperidino-pentyl)-amine 
• 109399-76-0 2-((Z)-3,4-diethoxy-benzylidene)-6-hydroxy-4-methoxy-benzofuran-3-one 
• 75332-49-9 3,4-diethoxy-trans-cinnamic acid ethyl ester 
• 94712-09-1 7-chloro-3-(3,4-diethoxy-phenyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 
• 32640-09-8 4-amino-2-(3,4-diethoxy-phenyl)-7-methoxy-chromeno[4,3-d]pyrimidin-5-one 
• 197632-12-5 3',4'-diethoxy-4-stilbazole 
• 284044-41-3 (3-benzyloxy-4-cyano-phenylamino)-(3,4-ethoxy-phenyl)-acetic acid methyl ester 
• 1426297-86-0 (3R,4R)-3-(4-benzyloxy-3-methoxybenzyl)-4-(3,4-diethoxybenzyl)dihydrofuran-2-one 
• 1426297-87-1 (3R,4R)-3-(4-benzyloxy-3-ethoxybenzyl)-4-(3,4-diethoxybenzyl)dihydrofuran-2-one 
• 1426297-95-1 C₂₃H₂₈O₆ 
• 1426297-96-2 C₂₄H₃₀O₆ 
• 1426297-99-5 2-(3,4-diethoxybenzyl)malonic acid diethyl ester 

Relevant articles and documents

Modular logic gates: Cascading independent logic gates via metal ion signals

Systematic cascading of molecular logic gates is an important issue to be addressed for advancing research in this field. We have demonstrated that photochemically triggered metal ion signals can be utilized towards that goal. Thus, independent logic gates were shown to work together while keeping their identity in more complex logic designs. Communication through the intermediacy of ion signals is clearly inspired from biological processes modulated by such signals, and implemented here with ion responsive molecules.

In vitro study and structure-activity relationship analysis of stilbenoid derivatives as powerful vasorelaxants: Discovery of new lead compound

The development of vasorelaxant as the antihypertensive drug is important as it produces a rapid and direct relaxation effect on the blood vessel muscles. Resveratrol (RV), as the most widely studied stilbenoid and the lead compound, inducing the excellent vasorelaxation effect through the multiple signalling pathways. In this study, the in vitro vascular response of the synthesized trans-stilbenoid derivatives, SB 1-8e were primarily evaluated by employing the phenylephrine (PE)-precontracted endothelium-intact isolated aortic rings. Herein we report trans-3,4,4′-trihydroxystilbene (SB 8b) exhibited surprisingly more than 2-fold improvement to the maximal relaxation (Rmax) of RV. This article also highlights the characterization of the aromatic protons in terms of their unique splitting patterns in 1H NMR.

Synthesis and antitumor evaluation of arctigenin derivatives based on antiausterity strategy

A series of new (-)-arctigenin derivatives with variably modified O-alkyl groups were synthesized and their preferential cytotoxicity was evaluated against human pancreatic cancer cell line PANC-1 under nutrient-deprived conditions. The results showed that monoethoxy derivative 4i (PC50, 0.49 μM), diethoxy derivative 4h (PC50, 0.66 μM), and triethoxy derivative 4m (PC50, 0.78 μM) showed the preferential cytotoxicities under nutrient-deprived conditions, which were identical to or more potent than (-)-arctigenin (1) (PC50, 0.80 μM). Among them, we selected the triethoxy derivative 4m and examined its in vivo antitumor activity using a mouse xenograft model. Triethoxy derivative 4m exhibited also in vivo antitumor activity with the potency identical to or slightly more than (-)-arctigenin (1). These results would suggest that a modification of (-)-arctigenin structure could lead to a new drug based on the antiausterity strategy.