135181-96-3Relevant academic research and scientific papers
4-Phenyl quinoline derivatives as potential serotonin receptor ligands with antiproliferative activity
Joshi, Pranaya V.,Sayed, Alim A.,RaviKumar, Ameeta,Puranik, Vedavati G.,Zinjarde, Smita S.
, p. 246 - 258 (2017/05/12)
Antagonists of signaling receptors are often effective non-toxic therapeutic agents. Over the years, there have been evidences describing the role of serotonin or 5-hydroxytryptamine (5-HT) in development of cancer. Although there are reports on the antip
Alkyltriflate-triggered annulation of arylisothiocyanates and alkynes leading to multiply substituted quinolines through domino electrophilic activation
Zhao, Peng,Yan, Xiaoyu,Yin, Hang,Xi, Chanjuan
, p. 1120 - 1123 (2014/03/21)
The reaction of arylisothiocyanate, alkyltriflate, and alkynes leads to variously substituted quinolines in high yields. The reaction undergoes alkyltriflate-triggered domino electrophilic activation and avoids the use of a transition-metal catalyst. A variety of functional groups are tolerated in the quinoline ring.
An efficient synthesis of 4-phenyl-2-aminoquinolines
Sayed
, p. 749 - 756 (2007/10/02)
An efficient procedure for 3-substituted-4-Phenyl-2-aminoquinolines involving the reaction between a preformed complex of amide 2 and phosphorus oxychloride with o-acetamidobenzophenone is reported. Hitherto unknown ten 4-Phenyl-2-aminoquinolines have bee
