30668-14-5

Basic information

• Product Name: 1-MORPHOLINOPROPAN-1-ONE
• Synonyms: 1-MORPHOLINOPROPAN-1-ONE;1-(4-Morpholinyl)-1-propanone
• CAS NO: 30668-14-5
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.18
• Mol File: 30668-14-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 269.5°Cat760mmHg
• Flash Point: >110℃
• Appearance: /
• Density: 1.068 g/mL at 25 °C
• Vapor Pressure: 0.00723mmHg at 25°C
• Refractive Index: 1.461
• CAS DataBase Reference: 1-MORPHOLINOPROPAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-MORPHOLINOPROPAN-1-ONE(30668-14-5)
• EPA Substance Registry System: 1-MORPHOLINOPROPAN-1-ONE(30668-14-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 30668-14-5(Hazardous Substances Data)

Usage

General Description

1-Morpholinopropan-1-one, also known as MPO, is a chemical compound with the molecular formula C7H13NO2. It is a versatile intermediate used in the production of various compounds such as pharmaceuticals, agrochemicals, and other organic synthesis. MPO is commonly found in research laboratories and chemical industries due to its unique chemical properties and reactivity. It is often used as a building block in the synthesis of heterocyclic compounds and as a solvent in various chemical reactions. Additionally, MPO has applications in the production of polymers and as a reagent in organic chemistry. As a result of its diverse uses, 1-Morpholinopropan-1-one plays a significant role in the creation of a wide range of products across different industries.

InChI:InChI=1/C7H13NO2/c1-2-7(9)8-3-5-10-6-4-8/h2-6H2,1H3

Upstream product

• 110-91-8 morpholine 
• 4799-68-2 3-benzyloxypropan-1-ol 
• 5117-12-4 N-Acryloylmorpholine 
• 591-50-4 iodobenzene 

Downstream Products

• 5117-12-4 N-Acryloylmorpholine 
• 19307-74-5 1-phenyl-pent-1-yn-3-one 
• 128084-44-6 1-(dimethyl(phenyl)silyl)propan-1-one 
• 5117-13-5 2-methyl-1-morpholinoprop-2-en-1-one 
• 155222-99-4 1-(4-morpholinyl)-2-phenyl-1-propanone 
• 816-40-0 1-Bromo-2-butanone 
• 23949-50-0 4-propyl-morpholine 
• 1073-26-3 2-propionylpyrrole 
• 135181-96-3 4-(3-methyl-4-phenylquinolin-2-yl)morpholine 
• 31597-37-2 4-(6-chloro-3-methyl-4-phenyl-2-quinolyl)morpholine 

Relevant articles and documents

Catalytic α-Hydroarylation of Acrylates and Acrylamides via an Interrupted Hydrodehalogenation Reaction

The palladium-catalyzed, α-selective hydroarylation of acrylates and acrylamides is reported. Under optimized conditions, this method is highly tolerant of a wide range of substrates including those with base sensitive functional groups and/or multiple enolizable carbonyl groups. A detailed mechanistic study was undertaken, and the high selectivity of this transformation was shown to be enabled by the formation of a [PdII(Ar)(H)] intermediate, which performs selective hydride insertion into the β-position of α,β-unsaturated carbonyl compounds.

Selective catalytic sp3 C-O bond cleavage with C-N bond formation in 3-alkoxy-1-propanols

The ruthenium catalyzed selective sp3 C-O cleavage with amide formation was reported in reactions of 3-alkoxy-1-propanol derivatives and amines. The cleavage only occurs at the C3-O position even with 3-benzyloxy-1-propanol. Based on the experimental results, O-bound and C-bound Ru enolate complexes were proposed as key intermediates for the unique selective sp3 C-O bond cleavage in 3-alkoxy-1-propanols.