1351958-83-2Relevant academic research and scientific papers
Pyrazolo-fused 4-azafluorenones as key reagents for the synthesis of fluorescent dicyanovinylidene-substituted derivatives
Orrego-Hernández, Jessica,Lizarazo, Carolina,Cobo, Justo,Portilla, Jaime
, p. 27318 - 27323 (2019/09/12)
A green process to access pyrazolo-fused 4-azafluorenones (indeno[1,2-b]pyrazolo[4,3-e]pyridines, IPP) 4a-xvia the three-component reaction between indan-1,3-dione (1), benzaldehydes 2 and 5-amino-1-arylpyrazoles 3 is described. These compounds were successfully used as precursors of the novel dicyanovinylidene derivatives 7a-d containing different acceptor (A) or donor (D) aryl groups at position 4 of its fused system. The structures of products obtained (4a-x and 7a-d) were determined based on NMR experiments, HRMS analysis, and X-ray diffraction studies for 7b. The photophysical and computational studies of 7a-d showed that these products are modulable ICT fluorophores, even some preliminary tests revealed that these compounds could be used as fluorescent chemodosimeters for cyanide detection.
A π-stacked chain of hydrogen-bonded dimers in 3-tert-butyl-1-(4-chloro- phen-yl)-4-phenyl-indeno-[1,2-b]pyrazolo-[4,3-e]pyridin-5(1H)-one and a π-stacked sheet of hydrogen-bonded chains in 3-tert-butyl-1-(4-chloro-phen- yl)-4-(4-meth-oxy-phen-yl)indeno-[
Portilla, Jaime,Lizarazo, Carolina,Cobo, Justo,Glidewell, Christopher
experimental part, p. o479-o483 (2012/01/12)
In 3-tert-butyl-1-(4-chloro-phen-yl)-4-phenyl-indeno-[1,2-b]pyra-zolo-[4,3- e]pyridin-5(1H)-one, C29H22ClN3O, (I), inversion-related pairs of mol-ecules are linked by C - H...O hydrogen bonds to form R 22/
