1351997-27-7

Downstream Products

• 1351997-26-6 6-fluoro-3-{2-[2-(tetrahydro-pyran-2-yloxy)-ethylsulfanyl]-phenyl}-[1, 2,4]-triazolo[4,3-a]pyridine 
• 1351997-28-8 (1S,4S)-4-(3-{2-[2-(tetrahydro-pyran-2-yloxy)ethylsulfanyl]phenyl}-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydronaphthalen-1-ylamine 
• 1351997-29-9 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[(1S,4S)-4-(3-{2-[2-(tetrahydropyran-2-yloxy)ethyIsuIfanyI]phenyl}-[1,2,4]triazoIo[4,3-a]pyridin-6-yIoxy)-1,2,3,4-tetrahydronaphthalen-1-yl]urea 
• 1351997-11-9 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-((1S,4S)-4-{3-[2-(2-hydroxy-ethylsulfanyl)-phenyl]-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy}-1,2,3,4-tetrahydro-naphthalen-1-yl)-urea 
• 1443252-60-5 6-fluoro-3-{2-[(2-{triisopropylsilanyloxy}ethyl)sulfanyl]phenyl}-[1,2,4]triazolo[4,3-a]pyridine 

Relevant academic research and scientific papers

KINASE INHIBITORS

Disclosed are compounds having [1,2,4]triazolo[4,3-a]pyridine groups and pharmaceutically acceptable salts thereof. The compounds are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.

DERIVATIVES OF 4-HYDROXY-1,2,3,4-TETRAHYDRONAPHTALEN-1-YL UREA AND THEIR USE IN THE TREATMENT OF, INTER ALIA, DISEASES OF THE RESPIRATORY TRACT

Disclosed are compounds having [1,2,4]triazolo[4,3-a] pyridine groups and pharmaceutically acceptable salts thereof. The compounds are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.