1351997-11-9

Upstream product

• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 317806-87-4 2,2,2-trichloroethyl 3-tert-butyl-1-p-tolyl-1H-pyrazol-5-ylcarbamate 
• 1351997-28-8 (1S,4S)-4-(3-{2-[2-(tetrahydro-pyran-2-yloxy)ethylsulfanyl]phenyl}-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydronaphthalen-1-ylamine 
• 1351997-26-6 6-fluoro-3-{2-[2-(tetrahydro-pyran-2-yloxy)-ethylsulfanyl]-phenyl}-[1, 2,4]-triazolo[4,3-a]pyridine 
• 1351997-27-7 2-[2-(6-fluoro-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-phenylsulfanyl]-ethanol 
• 1351997-29-9 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[(1S,4S)-4-(3-{2-[2-(tetrahydropyran-2-yloxy)ethyIsuIfanyI]phenyl}-[1,2,4]triazoIo[4,3-a]pyridin-6-yIoxy)-1,2,3,4-tetrahydronaphthalen-1-yl]urea 

Relevant academic research and scientific papers

UREA DERIVATIVES AND THEIR THERAPEUTIC USE IN THE TREATMENT OF, INTER ALIA, DISEASES OF THE RESPIRATORY TRACT

Compounds of formula (I) are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory wherein R1 is a radical of formula (IA) or (IB) or (IC): 10 Y is -0- or —S(0)p- wherein

UREA DERIVATIVES AND THEIR THERAPEUTIC USE IN THE TREATMENT OF, INTER ALIA, DISEASES OF THE RESPIRATORY TRACT

Compounds of formula (I) are p38 MAPK inhibitors, useful as anti- inflammatory agents in the treatment of, inter alia, diseases of the respiratory wherein R1 is a radical of formula (IA) or (IB) or (IC): 10 Y is -0- or -S(0)p- wherei