135204-37-4

Basic information

• Product Name: (4R,5S)-3-acetyl-2,2-dimethyl-4-(hydroxymethyl)-5-<4-(methylthio)phenyl>-1,3-oxazolidine
• Synonyms: (4R,5S)-3-acetyl-2,2-dimethyl-4-(hydroxymethyl)-5-<4-(methylthio)phenyl>-1,3-oxazolidine
• CAS NO: 135204-37-4
• Molecular Weight: 295.403
• Mol File: 135204-37-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4R,5S)-3-acetyl-2,2-dimethyl-4-(hydroxymethyl)-5-<4-(methylthio)phenyl>-1,3-oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-3-acetyl-2,2-dimethyl-4-(hydroxymethyl)-5-<4-(methylthio)phenyl>-1,3-oxazolidine(135204-37-4)
• EPA Substance Registry System: (4R,5S)-3-acetyl-2,2-dimethyl-4-(hydroxymethyl)-5-<4-(methylthio)phenyl>-1,3-oxazolidine(135204-37-4)

Safety Data

• Hazardous Substances Data: 135204-37-4(Hazardous Substances Data)

Upstream product

• 135204-36-3 (4S,5S)-3-acetyl-2,2-dimethyl-4-formyl-5-<4-(methylthio)phenyl>-1,3-oxazolidine 
• 16854-32-3 (1S,2S)-(+)-thiomicamine 
• 135204-33-0 (4S,5S)-5-(4-methylthiophenyl)-4-acetoxymethyl-3-acetyl-2,2-dimethyl-1,3-oxazolidine 
• 135204-34-1 (4S,5S)-3-acetyl-2,2-dimethyl-4-(hydroxymethyl)-5-<4-(methylthio)phenyl>-1,3-oxazolidine 
• 135204-35-2 (4R,5S)-3-acetyl-2,2-dimethyl-4-formyl-5-<4-(methylthio)phenyl>-1,3-oxazolidine 
• 135204-38-5 (4S,5S)-5-(4-methylthiophenyl)-4-hydroxymethyl-2,2-dimethyl-1,3-oxazolidine 

Downstream Products

• 27348-48-7 (+)-(1S,2R)-2-amino-1-<4-(methylthio)phenyl>-1,3-propanediol 
• 23150-35-8 (R*,R*)-(+)-thiomicamine 
• 135761-10-3 Acetic acid (R)-2-methyl-5-(4-methylsulfanyl-phenyl)-4,5-dihydro-oxazol-4-ylmethyl ester; compound with methanesulfonic acid 
• 135204-55-6 (4R,5S)-4-(acetoxymethyl)-3-acetyl-2,2-dimethyl-5-<4-(methylthio)phenyl>-1,3-oxazolidine 

Relevant articles and documents

Process for the stereochemical inversion of (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R) enantiomers

A four step process for transforming (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R)-enantiomers is described. The final compounds are useful intermediates for the synthesis of antibiotics like Chloramphenicol, Thiamphenicol and Florfenicol. The starting products generally are discard products in the synthesis of said antibiotics.

Process for the stereochemical inversion of (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R) enantiomers

A four step process for transforming (2S,3S)-2-amino-3-phenyl-1,3--propanediols into their (2R,3R)-enantiomers is described. The final compounds are useful intermediates for the synthesis of antibiotics like Chloramphenicol, Thiamphenicol and Florfenicol. The starting products generally are discard products in the syn-thesis of said antibiotics.