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23150-35-8

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23150-35-8 Usage

General Description

[R(R*,R*)]-2-amino-1-[p-(methylthio)phenyl]propane-1,3-diol, also known as Mephedrone, is a synthetic stimulant drug. It belongs to the class of cathinones and has similar effects to drugs like ecstasy and cocaine. This chemical is known for producing feelings of euphoria, increased energy, and heightened sociability. It can also cause hallucinations, paranoia, and agitation. Mephedrone is usually found in the form of white powder, capsules, or crystals and is often snorted, ingested, or injected. It is classified as a controlled substance in many countries due to its potential for abuse and addiction.

Check Digit Verification of cas no

The CAS Registry Mumber 23150-35-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,5 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 23150-35:
(7*2)+(6*3)+(5*1)+(4*5)+(3*0)+(2*3)+(1*5)=68
68 % 10 = 8
So 23150-35-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H15NO2S/c1-14-8-4-2-7(3-5-8)10(13)9(11)6-12/h2-5,9-10,12-13H,6,11H2,1H3

23150-35-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [R(R*,R*)]-2-amino-1-[p-(methylthio)phenyl]propane-1,3-diol

1.2 Other means of identification

Product number -
Other names N-Boc-D-Phenylglycine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23150-35-8 SDS

23150-35-8Relevant articles and documents

Synthesis of 4-sulfur-substituted (2S,3R)-3-phenylserines by enzymatic resolution. Enantionure precursors for thiamphenicol and florfenicol

Kaptein, Bernard,Van Dooren, Thei J.G.M.,Boesten, Wilhelmus H. J.,Sonke, Theo,Duchateau, Alexander L.L.,Broxterman, Quirinus B.,Kamphuis, Johan

, p. 10 - 17 (2013/09/08)

Enantiomerically pure 4-methylthio- and 4-methylsulfonylsubstitutcd (2S,3R)-3-phenylserines are prepared by enzymatic resolution of the corresponding racemic threo amides using the amidase from Ochrobactrum anthropi NCIMB 40321. The unwanted (2R,3S) enantiomers of the amides are separated from the enantiopure amino acids and easily racemized after Schiff base formation with the corresponding 4-(methylthio)- and 4-(methylsulfonyl)benzaldehyde. The racemization can be combined with the preparation of the racemic amides by aldol reaction under crystallization conditions to yield only the threo isomers. Enantiopure (25,3R)-3-[4-(methylthio)phenyl]serine and (2S,3R)-3-[4-(methylsulfonyl)phenyl]serine are thus obtained in 78% and 62% overall yields starting from the corresponding substituted benzaldehydes. (2S,3A)-3-[4-(Methylthio)phenyl]serine is reduced to (1R,2R)-2-amino-1-[4-(methylthio)phenyl]propane-1,3-diol with NaBH4/H2SO4 and can be used for the synthesis of thiamphenicol and florfenicol.

Asymmetric synthesis using sulfinimines (thiooxime S-oxides)

Davis, Franklin A.,Portonovo, Padma S.,Reddy, Rajarathnam E.,Reddy, G. Venkat,Zhou, Ping

, p. 291 - 303 (2007/10/03)

The addition of diethylaluminum cyanide and the lithium enolate of methyl α-bromoacetate to sulfinimines (thiooxime S-oxides) is highly diastereoselective affording α-amino nitriles and N-sulfinylaziridines, respectively. Hydrolysis of the α-amino nitriles gives α-amino acids in high ee, while hydrolysis of N-sulfinylaziridine carboxylic acids give β-hydroxy-α-amino acids. The latter compounds were transformed into (+)-thiamphenicol, a broad spectrum antibiotic and sphingosine, an important component of the sphingolipids.

Process for the stereochemical inversion of (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R) enantiomers

-

, (2008/06/13)

A four step process for transforming (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R)-enantiomers is described. The final compounds are useful intermediates for the synthesis of antibiotics like Chloramphenicol, Thiamphenicol and Florfenicol. The starting products generally are discard products in the synthesis of said antibiotics.

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