135205-82-2

Usage

Uses

Used in Pharmaceutical Industry:
(1-isopropyl-1H-imidazol-2-yl)methanol (SALTDATA: FREE) is used as a pharmaceutical intermediate for the synthesis of various drugs and active pharmaceutical ingredients. Its imidazole ring and isopropyl group may contribute to the development of new therapeutic agents with unique mechanisms of action.
Used in Chemical Research and Development:
In the field of chemical research and development, (1-isopropyl-1H-imidazol-2-yl)methanol (SALTDATA: FREE) serves as a valuable compound for studying its reactivity, stability, and potential applications in the synthesis of novel chemical entities. Its structural features may provide insights into new reaction pathways and the creation of innovative materials.
Used in Material Science:
(1-isopropyl-1H-imidazol-2-yl)methanol (SALTDATA: FREE) may be utilized in material science for the development of new materials with specific properties. Its imidazole ring and isopropyl group could play a role in the design of materials with tailored characteristics, such as improved stability, reactivity, or selectivity, for various applications.

Upstream product

• 53332-64-2 N-isopropyl-1H-imidazole-2-carboxaldehyde 

Downstream Products

• 497851-79-3 4-{[(1-isopropyl-1H-imidazol-5-yl)methyl]sulfanyl}aniline 
• 497850-17-6 7-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-N-({4-[(1-isopropyl-1H-imidazol-2-yl)methyl]sulfanyl}phenyl)-2,3-dihydro-1H-1-benzazepine-4-carboxamide 

Relevant academic research and scientific papers

Orally active CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological activities of 1-benzazepine derivatives containing a sulfoxide moiety

In order to develop orally active CCR5 antagonists, 1-propyl- or 1-isobutyl-1-benzazepine derivatives containing a sulfoxide moiety have been designed, synthesized, and evaluated for their biological activities. Sulfoxide compounds containing a 2-pyridyl

BENZAZEPINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE

The present invention provides a novel benzazepine derivative represented by formula : wherein, R1 is a 5- or 6-membered aromatic ring, R2 is lower alkyl group, etc., Y is an optionally substituted imino group, ring A and ring B are independently an optionally substituted aromatic ring, W is formula -W1-X2-W2- (W1 and W2 are independently S(O)m1 (m1 is 0, 1 or 2), etc., and X2 is an optionally substituted alkylene groupetc. ), a preparation method and use thereof.

Optically active antifungal azoles. III. Synthesis and antifungal activity of sulfide and sulfonamide derivatives of (2R,3R)-2-(2,4-difluorophenyl)-3- mercapto-1-(1H-1,2,4-triazol-1-yl)-2-butanol

In an effort to find potent antifungal agents, optically active sulfur- containing triazole derivatives, sulfides (3) and sulfonamides (4), were prepared and evaluated for antifungal activity against Candida albicans in vitro and in vivo. The sulfides (3) were prepared by the reaction of (2R,3R)- 2-(2,4-difluorophenyl)-3-mercapto-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1) with various heteroarylmethyl chlorides in the presence of sodium methoxide. The sulfonamides (4) were synthesized starting from the disulfide (15) in three steps including oxidation of the corresponding sulfenamides (17). Some of the sulfur-containing triazole derivatives (3, 4) showed strong protective effects against candidosis in mice.