135210-01-4

Basic information

• Product Name: 2-chloro-4-nitrophenyl 4-nitrophenyl sulfide
• Synonyms: 2-chloro-4-nitrophenyl 4-nitrophenyl sulfide
• CAS NO: 135210-01-4
• Molecular Weight: 310.718
• Mol File: 135210-01-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-4-nitrophenyl 4-nitrophenyl sulfide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-4-nitrophenyl 4-nitrophenyl sulfide(135210-01-4)
• EPA Substance Registry System: 2-chloro-4-nitrophenyl 4-nitrophenyl sulfide(135210-01-4)

Safety Data

• Hazardous Substances Data: 135210-01-4(Hazardous Substances Data)

Upstream product

• 350-30-1 3-chloro-4-fluoronitrobenzene 
• 1849-36-1 para-nitrobenzenethiol 
• 99-54-7 3,4-dichloronitrobenzene 

Downstream Products

• 796089-68-4 (2-chloro-4-nitro-phenyl)-(4-nitro-phenyl)-sulfone 
• 34332-19-9 (4-amino-2-chloro-phenyl)-(4-amino-phenyl)-sulfone 

Relevant articles and documents

Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitors

A forward chemical genetic approach was followed to discover new targets and lead compounds for Parkinson's disease (PD) treatment. By analysis of the cell protection produced by some small molecules, a diphenyl sulfide compound was revealed to be a new phosphodiesterase 7 (PDE7) inhibitor and identified as a new hit. This result allows us to confirm the utility of PDE7 inhibitors as a potential pharmacological treatment of PD. On the basis of these data, a diverse family of diphenyl sulfides has been developed and pharmacologically evaluated in the present work. Moreover, to gain insight into the safety of PDE7 inhibitors for human chronic treatment, we evaluated the new compounds in a surrogate emesis model, showing nonemetic effects.