1352127-71-9Relevant academic research and scientific papers
Synthesis and Homologation of an Azetidin-2-yl Boronic Ester with α-Lithioalkyl Triisopropylbenzoates
Delany, Pascal K.,Hodgson, David M.
, p. 9981 - 9984 (2019)
An α-boryl azetidine, obtained by α-lithiation-borylation of N-Botc azetidine, undergoes reaction with α-triisopropylbenzoyloxy organolithiums to give homologated boronic esters that can be further oxidized, homologated, arylated, and deprotected to give
Use of alkyl 2,4,6-triisopropylbenzoates in the asymmetric homologation of challenging boronic esters
Larouche-Gauthier, Robin,Fletcher, Catherine J.,Couto, Irantzu,Aggarwal, Varinder K.
, p. 12592 - 12594 (2012/01/05)
(-)-Sparteine induced lithiation of primary 2,4,6-triisopropylbenzoates and subsequent homologation of boronic esters is reported. A comparative study with lithiated N,N-diisopropylcarbamates has demonstrated the superiority of the hindered benzoate. The Royal Society of Chemistry 2011.
