1352166-03-0

Basic information

• Product Name: C₁₃H₁₈INO₃S
• CAS NO: 1352166-03-0
• Molecular Weight: 395.261
• Mol File: 1352166-03-0.mol

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₈INO₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₈INO₃S(1352166-03-0)
• EPA Substance Registry System: C₁₃H₁₈INO₃S(1352166-03-0)

Safety Data

• Hazardous Substances Data: 1352166-03-0(Hazardous Substances Data)

Upstream product

• 73270-63-0 N-Allylalanine methyl ester 
• 1296866-33-5 (S)-N-allyl-N-(1-hydroxypropan-2-yl)-4-methylbenzenesulfonamide 

Relevant articles and documents

I2-mediated diversity oriented diastereoselective synthesis of amino acid derived trans-2,5-disubstituted morpholines, piperazines, and thiomorpholines

Diastereoselective trans-2,5-disubstituted amino acids derived diverse morpholines, piperazines and thiomorpholines were prepared in 30 min-1 h with high yields through iodine-mediated 6-exotrig type cyclization from a single common synthetic intermediate. The displacement of iodine with hydride ion gave a methyl substituent at the 2-position of morpholines which provides an additional opportunity for diversity oriented nucleophilic substitution on the rings as well as incorporation of substituents at the 5-position from amino acids constituents.