1352166-28-9Relevant academic research and scientific papers
Catalyst free annulative thioboration of unfunctionalized olefins
Yang, Zhantao,Yang, Chun-Hua,Chen, Shiqi,Chen, Xixi,Zhang, Litian,Ren, Huijun
, p. 12092 - 12095 (2017/11/14)
A direct and catalyst-free annulative thioboration of unfunctionalized olefins has been developed. In the presence of BCl3 as the sole boron source, the boryl group and thiol group are added to the C-C double bonds simultaneously. The boronic acids obtained can be protected to form synthetically ubiquitous pinacol boronate esters.
I2-mediated diversity oriented diastereoselective synthesis of amino acid derived trans-2,5-disubstituted morpholines, piperazines, and thiomorpholines
Bera, Saurav,Panda, Gautam
, p. 1 - 4 (2012/02/16)
Diastereoselective trans-2,5-disubstituted amino acids derived diverse morpholines, piperazines and thiomorpholines were prepared in 30 min-1 h with high yields through iodine-mediated 6-exotrig type cyclization from a single common synthetic intermediate. The displacement of iodine with hydride ion gave a methyl substituent at the 2-position of morpholines which provides an additional opportunity for diversity oriented nucleophilic substitution on the rings as well as incorporation of substituents at the 5-position from amino acids constituents.
