135219-71-5Relevant academic research and scientific papers
Poststatin, a new inhibitor of prolyl endopeptidase IV. The chemical synthesis of poststatin
Tsuda, Makoto,Muraoka, Yasuhiko,Nagai, Machiko,Takeuchi, Tomio,Aoyagi, Takaaki
, p. 287 - 291 (1996)
Total synthesis of poststatin was achieved by both liquid phase and solid phase methods. In both methods, the (2R,3S)-3-amino-2-hydroxyvaleric acid moiety was incorporated into protected pentapeptides, and was oxidized to (S)-3-amino-2-oxovaleric acid (po
