135220-15-4

Basic information

• Product Name: 4H-Imidazol-4-one, 3,5-dihydro-3-methyl-2-(phenylamino)-
• CAS NO: 135220-15-4
• Molecular Formula: C10H11N3O
• Molecular Weight: 189.217
• Mol File: 135220-15-4.mol

Chemical Properties

• CAS DataBase Reference: 4H-Imidazol-4-one, 3,5-dihydro-3-methyl-2-(phenylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Imidazol-4-one, 3,5-dihydro-3-methyl-2-(phenylamino)-(135220-15-4)
• EPA Substance Registry System: 4H-Imidazol-4-one, 3,5-dihydro-3-methyl-2-(phenylamino)-(135220-15-4)

Safety Data

• Hazardous Substances Data: 135220-15-4(Hazardous Substances Data)

Usage

Derivative of imidazole

Contains a five-membered ring with four carbon atoms and one nitrogen atom

Substitution

3,5-dihydro-3-methyl-2-(phenylamino)refers to the arrangement of methyl and phenylamino groups on the imidazole ring

Usage

Can be used in organic synthesis and drug development

Potential biological activities

May have potential biological activities that could be of interest in medicinal chemistry research

Upstream product

• 129505-80-2 2-phenylimino-4-imidazolidinone 
• 77-78-1 dimethyl sulfate 
• 129505-80-2 sodium salt of 2'-phenylglycocyamidine 
• 56128-54-2 2-(phenylimino)imidazolidin-4-one 
• 74-88-4 methyl iodide 
• 103-71-9 phenyl isocyanate 
• 103-72-0 phenyl isothiocyanate 
• 74-89-5 methylamine 

Relevant articles and documents

Synthesis of a library of imidazolin-4-ones using poly(ethylene glycol) as soluble support

A library of imidazolin-4-ones has been synthesized using poly(ethylene glycol) (PEG) as soluble polymer support. The imidazolin-4-ones 6 or 7 were synthesized effectively by reaction of primary amine with PEG-supported carbodiimides 4, which were obtaine

THE FORMATION OF PYRAZINES FROM N-β-KETOIMINOTRIPHENYLPHOSPHORANES; IMINOPHOSPHORANE-MEDIATED SYNTHESES OF 2,2,4,4-TETRAPHENYL-N,N'-BIS(2-PENTANE-3-ON)-CYCLOBUTANE-1,3-DIIMINE; 1,3,4-OXADIAZOLES; 2-AMINO-3,5-DIHYDROIMIDAZOL-4-ONES; AND 2-DIPHENYLMETHYL-1,5-DIHYDROIMIDAZOL-4-ONE

The aza-Wittig reaction has been applied to the synthesis of the unstable N-β-keto ketenimine (18), which dimerize spontaneously, forming the very sterically hindered 2,2,4,4-tetraphenyl-N,N'-bis (2-pentane-3-on)-cyclobutane-1,3-diimine (21).Iminophosphoranes (33) and (38) are used for the preparation of some novel 1,5 and 3,5-dihydroimidazol-4-ones (36), (41a-b), (42).N-acylamino iminotriphenylphosphoranes (2a-d) are applied for the syntheses of a series of 1,3,4-oxadiazoles (32).The mechanism of the decomposition of the unstable N-β-keto iminotriphenylphosphoranes (1) into pyrazines and triphenylphosphine oxide has been investigated.Key words: Iminophosphoranes; β-keto carbodiimides; N-β-keto ketenimines; heterocycles.

TAUTOMERISM AND METHYLATION OF 2-IMINO-4-IMIDAZOLIDINONES

5-Benzylidenecreatinine and 2'-phenylglycocyamidine exist in DMSO-D6 in the imino form.In basic medium, the two compounds exhibit a dual reactivity with respect to methylating agents, forming N(2')- and N(3)-methyl derivatives.

HETEROGENEOUS METHYLATION OF THE SODIUM SALT OF 2-PHENYLIMINO-4-IMIDAZOLIDINONE BY DIMETHYL SULFATE IN ACETONITRILE

The sodium salt of 2-phenylimino-4-imidazolidinone, which exists in acetonitrile in the form of high-molecular agglomerates of spherical form 30-200 nm in diameter, reacts with dimethyl sulfate to form the isomeric exo- and endo-methylation products.Analysis of the kinetic parameters of nucleophilic substitution shows that it takes place on the surface of the agglomerates, i.e., is heterogeneous.