1352213-67-2

Upstream product

• 696-62-8 para-iodoanisole 
• 170751-31-2 4-methyl-N-(3-phenylprop-2-yn-1-yl)-N-(prop-2-yn-1-yl)benzenesulfonamide 
• 924906-80-9 Methanesulfonic acid 3-(4-methoxy-phenyl)-prop-2-ynyl ester 
• 37614-59-8 4-(4-methoxyphenyl)prop-2-yn-1-ol 
• 55022-46-3 4-methyl-N-prop-2-ynylbenzenesulfonamide 
• 173019-85-7 3-bromo-1-(4-methoxyphenyl)propyne 
• 305837-95-0 4-methyl-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide 
• 591-50-4 iodobenzene 

Downstream Products

• 1599470-85-5 6-methoxy-4-phenyl-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole 
• 1599470-86-6 4-(4-methoxyphenyl)-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole 
• 1352213-84-3 7-(4-methoxyphenyl)-11-phenyl-9-tosyl-9,10-dihydro-8H-pyrrolo[3,4-j]phenanthridine 

Relevant academic research and scientific papers

Selectivity in Garratt-Braverman cyclization of aryl-/heteroaryl- substituted unsymmetrical bis-propargyl systems: Formal synthesis of 7′-desmethylkealiiquinone

Unsymmetrical bis-propargyl ethers and sulfonamides containing various combinations of aryl/heteroaryl substituents at the acetylene termini were synthesized, and their reactivity under basic conditions was studied. Moderate to high (chemo)selectivity was

Synthesis of polycyclic isoindoline derivatives via tandem Pd-catalyzed coupling, propargyl-allenyl isomerization, [4 + 2] cycloaddition and aromatization reaction

We report in this paper an interesting sequential reaction involving sequential Sonogashira coupling, propargyl-allenyl isomerization, [4 + 2] cycloaddition and aromatization reaction, which provides a facile method for the synthesis of a variety of polycyclic isoindoline derivatives from easily accessible starting materials.