1352328-67-6 Usage
Description
Benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate is a bile acid derivative characterized by the presence of hydroxyl groups at the 3α and 7α positions, an ethyliden substituent at the 6 position, and an ester linkage at the 24 position. Its unique structure and arrangement of carbon atoms in the steroid ring system contribute to its biological activity, making it a promising candidate for pharmaceutical or medical applications.
Uses
Used in Pharmaceutical Industry:
Benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate is used as a pharmaceutical compound for its potential physiological effects. The specific functional groups and the arrangement of carbon atoms in its steroid ring system may contribute to its therapeutic properties, making it a valuable asset in the development of new drugs.
Used in Medical Industry:
In the medical field, benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate may be utilized for its potential applications in treating various health conditions. Its unique structure and biological activity could be harnessed to develop targeted therapies or diagnostic tools, enhancing patient care and outcomes.
Used in Drug Development:
Benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate is used as a key component in drug development, where its unique structure and functional groups can be leveraged to create novel therapeutic agents. Researchers can explore its potential in modulating biological pathways or targeting specific receptors, leading to the discovery of new treatments for various diseases.
Used in Diagnostic Applications:
In the diagnostic industry, benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate may be employed as a biomarker or a component in diagnostic assays. Its unique properties could be utilized to detect or monitor certain health conditions, providing valuable insights for clinicians and patients alike.
Used in Nutritional Supplements:
Given its role in the digestion and absorption of dietary fats, benzyl 3α,7α-dihydroxy-6-ethyliden-5β-cholan-24-oate may also find applications in the development of nutritional supplements. It could be incorporated into formulations to support healthy digestion and enhance the bioavailability of fat-soluble nutrients.
Check Digit Verification of cas no
The CAS Registry Mumber 1352328-67-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,2,3,2 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1352328-67:
(9*1)+(8*3)+(7*5)+(6*2)+(5*3)+(4*2)+(3*8)+(2*6)+(1*7)=146
146 % 10 = 6
So 1352328-67-6 is a valid CAS Registry Number.
1352328-67-6Relevant articles and documents
Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei
Sepe, Valentina,Ummarino, Raffaella,Dauria, Maria Valeria,Chini, Maria Giovanna,Bifulco, Giuseppe,Renga, Barbara,Damore, Claudio,Debitus, Cécile,Fiorucci, Stefano,Zampella, Angela
, p. 84 - 93 (2012)
We report the isolation and pharmacological characterization of conicasterol E isolated from the marine sponge Theonella swinhoei. Pharmacological characterization of this steroid in comparison to CDCA, a natural FXR ligand, and 6-ECDCA, a synthetic FXR agonist generated by an improved synthetic strategy, and rifaximin, a potent PXR agonist, demonstrated that conicasterol E is an FXR modulator endowed with PXR agonistic activity. Conicasterol E induces the expression of genes involved in bile acids detoxification without effect on the expression of small heterodimer partner (SHP), thus sparing the expression of genes involved in bile acids biosynthesis. The relative positioning in the ligand binding domain of FXR, explored through docking calculations, demonstrated a different spatial arrangement for conicasterol E and pointed to the presence of simultaneous and efficient interactions with the receptor. In summary, conicasterol E represents a FXR modulator and PXR agonist that might hold utility in treatment of liver disorders.
