135235-91-5Relevant academic research and scientific papers
SYNTHESIS OF 3-AMINO-4,4,4-TRIFLUORO-3-PHENYLBUTYRIC ACID
Kolycheva, M. T.,Gerus, I. I.,Yagupol'skii, Yu. L.,Kukhar', V. P.
, p. 101 - 104 (2007/10/02)
By the action of bis(trifluoroacetic) anhydride on 2,2,2-trifluoroacetophenone imine in the presence of pyridine the N-(trifluoroacetyl) derivative of the imine is formed, and this reacts with alkyl vinyl ethers and with ketene with the formation, respectively, of dihydro-1,3-oxazines and of a dihydro-1,3-oxazin-6(6H)-one.The latter is converted by hydrolysis with dilute and with concentrated acids into 3-phenyl-N-(trifluoroacetyl)-3-(trifluoromethyl)-β-alanine and the free acid.
N,N'-BIS(1-CHLOROALKYL)CARBODIIMIDES. III. REACTIONS OF N,N'-BIS(1-CHLOROALKYL)CARBODIIMIDES WITH CARBOXYLIC ACIDS
Fetyukhin, V. N.,Vovk, M. V.,Samarai, L. I.
, p. 1099 - 1103 (2007/10/02)
The reaction of N,N'-bis(1-chloroalkyl)carbodiimides with carboxylic acids has been studied.The initial reaction products are anhydrides of the carboxylic acids of N,N'-bisalkylideneureas.Under the conditions of the reaction the latter undergo further con
