87537-01-7

Upstream product

• 57959-52-1 1-chloro-1-phenyl-2,2,2-trifluoroethyl isocyanate 
• 76-05-1 trifluoroacetic acid 
• 45988-04-3 1-phenyl-2,2,2-trifluoroethylideneimine 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 135235-93-7 4,5-dihydro-2,4-bis(trifluoromethyl)-4-phenyl-1,3-oxazin-6(6H)-one 
• 135235-91-5 2,2,2-trifluoro-N-<2,2,2-trifluoro-1-phenyl-1-<(2,2,2-trifluoro-1-phenylethylidene)amino>ethyl>acetamide 
• 135235-95-9 6-butoxy-5,6-dihydro-4-phenyl-2,4-bis(trifluoromethyl)-4H-1,3-oxazine 
• 134329-14-9 Dipropyl <α-(2,2,2-trifluoroacetamido)-α-(trifluoromethyl)benzyl>phosphonate 
• 134329-12-7 Dimethyl <α-(2,2,2-trifluoroacetamido)-α-(trifluoromethyl)benzyl>phosphonate 
• 135235-94-8 3-phenyl-N-(trifluoroacetyl)-3-(trifluoromethyl)-β-alanine 
• 135235-90-4 3-phenyl-3-(trifluoromethyl)-β-alanine 
• 134329-13-8 Diethyl <α-(2,2,2-trifluoroacetamido)-α-(trifluoromethyl)benzyl>phosphonate 
• 135235-92-6 6-ethoxy-5,6-dihydro-4-phenyl-2,4-bis(trifluoromethyl)-4H-1,3-oxazine 

Relevant academic research and scientific papers

SYNTHESIS OF 3-AMINO-4,4,4-TRIFLUORO-3-PHENYLBUTYRIC ACID

By the action of bis(trifluoroacetic) anhydride on 2,2,2-trifluoroacetophenone imine in the presence of pyridine the N-(trifluoroacetyl) derivative of the imine is formed, and this reacts with alkyl vinyl ethers and with ketene with the formation, respectively, of dihydro-1,3-oxazines and of a dihydro-1,3-oxazin-6(6H)-one.The latter is converted by hydrolysis with dilute and with concentrated acids into 3-phenyl-N-(trifluoroacetyl)-3-(trifluoromethyl)-β-alanine and the free acid.

N,N'-BIS(1-CHLOROALKYL)CARBODIIMIDES. III. REACTIONS OF N,N'-BIS(1-CHLOROALKYL)CARBODIIMIDES WITH CARBOXYLIC ACIDS

The reaction of N,N'-bis(1-chloroalkyl)carbodiimides with carboxylic acids has been studied.The initial reaction products are anhydrides of the carboxylic acids of N,N'-bisalkylideneureas.Under the conditions of the reaction the latter undergo further con