1352497-01-8

Upstream product

• 556-56-9 allyl iodid 
• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 
• 106-95-6 allyl bromide 

Downstream Products

• 1352496-81-1 C₃₀H₅₀O₅Si 
• 1352496-83-3 C₃₀H₅₀O₅Si 
• 1352497-04-1 C₃₆H₆₄O₅Si₂ 

Relevant academic research and scientific papers

Syntheses of (+)-30-epi-, (-)-6-epi-, (±)-6,30-epi-13,14-Didehydroxyisogarcinol and (±)-6,30-epi-Garcimultiflorone A Utilizing Highly Diastereoselective, Lewis Acid-Controlled Cyclizations

The first syntheses of 13,14-didehydroxyisogarcinol (6) and garcimultiflorone A (5) stereoisomers are reported in six steps from a commercially available phloroglucinol. Lewis acid-controlled, diastereoselective cationic oxycyclizations enabled asymmetric syntheses of (-)-6-epi-6 and (+)-30-epi-6. A similar strategy enabled production of the meso-dervied isomers (±)-6,30-epi-6 and (±)-6,30-epi-5. Finally, a convenient strategy for gram scale synthesis was developed utilizing diastereomer separation at a later stage in the synthesis that minimized the number of necessary synthetic operations to access all possible stereoisomers.

Synthetic studies on soft coral norcembranolides: Total synthesis of (+)-10-epigyrosanolide e

Total synthesis of (+)-10-epigyrosanolide E was accomplished employing SmI2-mediated 5-exo cyclization of an aldehydo β-alkoxyvinyl sulfoxide and ring-closing metathesis reaction.