135253-38-2

Upstream product

• 135253-27-9 (S)-3-<2,2-Bis(methylthio)-1-cyclobutylcarbonyl>-1,3-oxazolidin-2-one 
• 135253-31-5 Methyl <(R),(E)-2-(t-butyldiphenylsiloxy)methyl-1-cyclobutylidene>acetate 
• 135253-30-4 Methyl <(R),(Z)-2-(t-butyldiphenylsiloxy)methyl-1-cyclobutylidene>acetate 
• 135253-33-7 Methyl <(R),(E)-2-(trimethylsiloxy)methyl-1-cyclobutylidene>acetate 
• 135253-35-9 Methyl <(R)-1-methyl-2-(trimethylsiloxy)methyl-1-cyclobutyl>acetate 
• 135253-36-0 Methyl <(R)-1-methyl-2-formyl-1-cyclobutyl>acetate 
• 135253-28-0 (S)-<2,2-Bis(methylthio)-1-cyclobutyl>methanol t-butyldiphenylsilyl ether 
• 135253-29-1 (S)-2-(((tert-butyldiphenylsilyl)oxy)methyl)cyclobutanone 
• 135356-00-2 Methyl (S)-2,2-bis(methylthio)cyclobutane-1-carboxylate 
• 135253-32-6 Methyl <(R),(E)-2-hydroxymethyl-1-cyclobutylidene>acetate 
• 135356-01-3 (S)-<2,2-Bis(methylthio)-1-cyclobutyl>methanol 
• 28117-19-3 (1R,6R)-2,6-Dimethyl-3-oxybicyclo<4.2.0>octan-4-one 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 26532-22-9 (1R, 2S)-grandisol 
• 135253-40-6 tert-Butyl-[2-((1R,2S)-2-isopropenyl-1-methyl-cyclobutyl)-ethoxy]-diphenyl-silane 
• 135253-39-3 (1R,2R)-2-<2-(t-Butyldiphenylsiloxy)ethyl>-2-methyl-1-cyclobutyl methyl ketone 

Relevant academic research and scientific papers

Enantio- and Diastereo-Selective Synthesis of (+)-Grandisol

(+)-Grandisol, an insect pheromone having cyclobutane skeleton, is synthesized enantio- and diastereoselectively.The key steps in the synthesis are the asymmetric cycloaddition reaction catalyzed by a chiral titanium reagent and the diastereoselective conjugate addition reaction by the combined use of Me2CuLi and trimethylsilyl trifluoromethanesulfonate.