1352621-90-9

Basic information

• Product Name: 1-bromo-2-(4-fluorophenylamino)ethanesulfonic acid 2,4,6-trichlorophenyl ester
• Synonyms: 1-bromo-2-(4-fluorophenylamino)ethanesulfonic acid 2,4,6-trichlorophenyl ester
• CAS NO: 1352621-90-9
• Molecular Weight: 477.566
• Mol File: 1352621-90-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-bromo-2-(4-fluorophenylamino)ethanesulfonic acid 2,4,6-trichlorophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-2-(4-fluorophenylamino)ethanesulfonic acid 2,4,6-trichlorophenyl ester(1352621-90-9)
• EPA Substance Registry System: 1-bromo-2-(4-fluorophenylamino)ethanesulfonic acid 2,4,6-trichlorophenyl ester(1352621-90-9)

Safety Data

• Hazardous Substances Data: 1352621-90-9(Hazardous Substances Data)

Upstream product

• 1352621-86-3 2,4,6-trichlorophenyl 1-bromoethenesulfonate 
• 371-40-4 4-fluoroaniline 
• 4790-35-6 ethenesulfonic acid 2,4,6-trichlorophenyl ester 
• 88-06-2 2,4,6-Trichlorophenol 

Downstream Products

• 1352622-02-6 1-bromo-2-[(4-fluorophenyl)methylamino]ethanesulfonic acid 2,4,6-trichlorophenyl ester 
• 116176-92-2 5-fluoro-1-methyl-1H-indole 
• 1352622-11-7 C₁₅H₁₃Cl₃FNO₃S 

Relevant articles and documents

A selective, tin-free radical mediated synthesis of indoles based on a sulfonate template

A synthesis of indoles based on a vinyl sulfonate template is described. The approach employs a sulfonate group which plays three discrete roles in the synthetic sequence. Firstly the highly electron-withdrawing sulfonate group behaves as an activating group for a 1,4-addition of an aniline to the unsaturated system. Secondly, the electron-withdrawing nature of the same group also allows it to behave as a radical stabilising group which facilitates radical cyclisation to an aromatic ring to yield a transient indoline. Finally, the pendant sulfonate group behaves as a leaving group to yield the indole.