1352624-90-8

Basic information

• Product Name: 5-Chloro-6-fluoro-3-(tetrahydro-2H-pyran-4-yl)-1,3-dihydro-2H-imidazo[4,5-b] pyridin-2-one
• Synonyms: 5-Chloro-6-fluoro-3-(tetrahydro-2H-pyran-4-yl)-1,3-dihydro-2H-imidazo[4,5-b] pyridin-2-one
• CAS NO: 1352624-90-8
• Molecular Weight: 271.679
• Mol File: 1352624-90-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-Chloro-6-fluoro-3-(tetrahydro-2H-pyran-4-yl)-1,3-dihydro-2H-imidazo[4,5-b] pyridin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-6-fluoro-3-(tetrahydro-2H-pyran-4-yl)-1,3-dihydro-2H-imidazo[4,5-b] pyridin-2-one(1352624-90-8)
• EPA Substance Registry System: 5-Chloro-6-fluoro-3-(tetrahydro-2H-pyran-4-yl)-1,3-dihydro-2H-imidazo[4,5-b] pyridin-2-one(1352624-90-8)

Safety Data

• Hazardous Substances Data: 1352624-90-8(Hazardous Substances Data)

Upstream product

• 33024-60-1 tetrahydro-2H-pyran-4-ylamine monohydrochloride 
• 82671-06-5 2,6-dichloro-5-fluoro-3-pyridinecarboxylic acid 

Relevant articles and documents

Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases

New pyridin-2(1h)-one derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

HETEROARYL IMIDAZOLONE DERIVATIVES AS JAK INHIBITORS

New heteroaryl imidazolone derivatives having the chemical structure of formula (I) disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).