1352640-64-2Relevant academic research and scientific papers
Aminobromination of β-nitrostyrene derivatives with N,N-dibromourethane as the aminobrominating reagent
Chen, Zhan-Guo,Zhao, Peng-Fei,Wang, Yun
experimental part, p. 5887 - 5893 (2011/11/06)
A concise and efficient aminobromination reaction for β-nitrostyrene derivatives by treatment with N,N-dibromourethane was developed. For the β-nitrostyrene derivatives, the aminobromination successfully proceeded at room temperature in CH3CN without catalysis or protection by an inert gas and gave products in excellent yields (80-97%). For the β-methyl analogs, the reaction proceeded smoothly with anhydrous K2CO 3 as a catalyst under the same conditions to provide the aminobrominated products in good yields (53-78%). A possible pathway for this electrophilic addition reaction is proposed.
