82040-74-2

Usage

Type of compound

Nitroaromatic compound

Structural features

Bromine atom
Two methoxy groups
Benzene ring
(E)-2-nitroethenyl group

Uses

Precursor in the synthesis of pharmaceuticals
Precursor in the synthesis of organic compounds
Potential building block for new materials and research chemicals

Physical state

Yellow crystalline solid

Molecular weight

289.10 g/mol

Hazard classification

Hazardous material

Safety measures

Special handling and storage precautions required

Potential risks

Toxicity and reactivity

Upstream product

• 75-52-5 nitromethane 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 1215288-64-4 1-acetylamino-1-(2-bromo-4,5-dimethoxyphenyl)-2,2-dibromo-2-nitroethane 
• 1352640-64-2 2,2-dibromo-1-(2-bromo-4,5-dimethoxyphenyl)-1-[(ethyoxycarbonyl)amino]-2-nitroethane 
• 1197893-75-6 3-[1-(2-bromo-4,5-dimethoxyphenyl)-2-nitroethyl]-2-phenyl-1H-indole 
• 145744-17-8 (E)-N-carbethoxy-N-(4'-methoxystyryl)-2-(2'-bromo-4',5'-dimethoxyphenyl)ethylamine 
• 145744-15-6 (E)-N-carbethoxy-N-styryl-2-(2'-bromo-4',5'-dimethoxyphenyl)ethylamine 
• 17889-64-4 N-Carbethoxy-2-bromo-4,5-dimethoxyphenylethylamine 
• 96839-24-6 N-(3,4-dimethoxybenzyl)-N'-methyl-2-(3,4-dimethoxyphenyl)ethanamine 
• 96025-46-6 N-methyl-N-benzyl-3,4-dimethoxyphenethylamine 
• 340829-13-2 5-[2-(3,4-dimethoxy-phenyl)-vinyl]-7,8-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester 
• 340829-11-0 5-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-7,8-dimethoxy-1-methyl-3,4-dihydroisoquinoline 
• 340829-12-1 5-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-7,8-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline 
• 340829-03-0 N-(2-{2-[2-(3,4-dimethoxy-phenyl)-vinyl]-4,5-dimethoxy-phenyl}-ethyl)-acetamide 
• 204002-24-4 7,8-Dimethoxy-1-methyl-5-((E)-styryl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester 
• 204002-21-1 N-{2-[4,5-Dimethoxy-2-((E)-styryl)-phenyl]-ethyl}-acetamide 

Relevant academic research and scientific papers

Synthesis of 3-arylindole derivatives from nitroalkane precursors

3-Arylindole derivatives were synthesized by Cu(i) catalysed intramolecular Ullmann coupling of 2-bromoarylaminoalkanes. 2-Bromoarylaminoalkanes were synthesized from 2-bromoarylnitroalkanes, which in turn prepared through AlCl3-mediated Friede

Photochemically induced cyclization of N-[2-(o-styryl)phenylethyl]acetamides and 5-styryl-1-methyl-1,2,3,4-tetrahydroisoquinolines: New total syntheses of 1-methyl-1,2,3,4-tetrahydronaphtho[2,1-f]isoquinolines

Two new total syntheses of 1-methyl-1,2,3,4-dihydronaphtho[1,2-f]isoquinolines are based on photochemically induced cyclization of N-{2-[(E)-2-phenyl-1-etheynyl]phenylethyl]}acetamides or 1-methyl-5-[(E)-2-phenyl-1-ethenyl]-1,2,3,4-tetrahydroisoquinolines.

An intramolecular aryne cycloaddition approach to phenanthrene alkaloids

A new synthesis of phenanthrene alkaloids which is based on the intramolecular Diels-Alder reaction between a styrene and an aryne is described.