1352732-72-9Relevant academic research and scientific papers
Enantioselective α-Carbonylative Arylation for Facile Construction of Chiral Spirocyclic β,β′-Diketones
Wu, Ting,Zhou, Qinghai,Tang, Wenjun
, p. 9978 - 9983 (2021)
We herein describe the first enantioselective α-carbonylative arylation, providing a diverse set of chiral spiro β,β′-diketones bearing various ring sizes and functionalities in high yields and good to excellent enantioselectivities. Calculations suggest the transformation proceeds through reductive elimination instead of nucleophilic addition pathway.
