1352755-86-2Relevant academic research and scientific papers
Asymmetric aerobic oxidative NHC-catalysed synthesis of dihydropyranones utilising a system of electron transfer mediators
Axelsson,Hammarvid,Ta,Sundén
supporting information, p. 11571 - 11574 (2016/10/03)
In the context of green chemistry, the replacement of high molecular weight stoichiometric oxidants with O2 is most desirable but difficult. Here, we report the asymmetric aerobic oxidative synthesis of dihydropyranones. The oxidation is aided by a system of electron transfer mediators and is selective toward the homoenolate. The dihydropyranones can be isolated in high to excellent yields, with high ee (up to 95%).
Direct β-activation of saturated aldehydes to formal michael acceptors through oxidative NHC catalysis
Mo, Junming,Shen, Liang,Chi, Yonggui Robin
supporting information, p. 8588 - 8591 (2013/09/12)
Without detours: Oxidative catalysis mediated by N-heterocyclic carbenes (NHCs) enables the direct β-carbon functionalization of saturated aldehydes (see scheme). The reaction proceeds through two sequential oxidative steps to generate α,β-unsaturated tri
N-heterocyclic carbene-catalyzed enantioselective annulation of bromoenal and 1,3-dicarbonyl compounds
Sun, Fang-Gang,Sun, Li-Hui,Ye, Song
supporting information; experimental part, p. 3134 - 3138 (2012/01/03)
Highly enantioselective [3+3]-annulation reactions of bromoenals and 1,3-dicarbonyl compounds are reported. In addition, both enantiomers of the resultant dihydropyranone could be easily obtained by choosing N-heterocyclic carbenes (NHCs) with the same stereocenter but different substituents under the optimized reaction conditions. Copyright
