13301-83-2Relevant articles and documents
Stereodivergent synthesis of 2-alkynyl buta-1,3-dienes using Sonogashira coupling with controllable retention or inversion of olefin geometry
Shakhmaev, Rinat N.,Ignatishina, Maria G.,Zorin, Vladimir V.
, (2020)
A stereodivergent approach to 2-alkynyl buta-1,3-dienes from a single stereoisomer of starting α-bromoenal has been developed. By simply switching the sequence of Sonogashira and Horner-Wadsworth-Emmons reactions, it is possible to obtain these branched d
FtsZ and QseC double-target antibacterial molecule as well as preparation method and application thereof
-
Paragraph 0074; 0088-0092, (2021/05/29)
The invention discloses an FtsZ and QseC double-target antibacterial molecule as well as a preparation method and application thereof. The structure of the antibacterial molecule is shown as a formula 1 defined in the description, wherein R1 is H, F, Cl,
PPh3·HBr-DMSO mediated expedient synthesis of γ-substituted β,γ-unsaturated α-ketomethylthioesters and α-bromo enals: Application to the synthesis of 2-methylsulfanyl-3(2 H)-furanones
Mal, Kanchan,Sharma, Abhinandan,Maulik, Prakas R.,Das, Indrajit
supporting information, p. 662 - 667 (2014/01/23)
An efficient chemoselective general procedure for the synthesis of γ-substituted β,γ-unsaturated α-ketomethylthioesters from α,β-unsaturated ketones has been achieved through an unprecedented PPh3·HBr-DMSO mediated oxidative bromination and Kornblum oxidation sequence. The newly developed reagent system serves admirably for the synthesis of α-bromoenals from enals. Furthermore, AuCl 3-catalyzed efficient access to 3(2H)-furanones from the above intermediates under extremely mild conditions are described. Copyright
