135277-65-5

Upstream product

• 13735-81-4 1-styrenyloxytrimethylsilane 
• 5296-64-0 allyl phenyl thioether 
• 108-98-5 thiophenol 
• 106-95-6 allyl bromide 
• 70-11-1 α-bromoacetophenone 
• 64878-08-6 2-(allylthio)-1-phenylethan-1-one 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 536-74-3 phenylacetylene 

Downstream Products

• 105621-13-4 2-phenyl-3-(phenylthio)furan 
• 174153-62-9 2-phenyl-3-(phenylthio)-1H-pyrrole 

Relevant academic research and scientific papers

Synthesis method of alpha-acyl homoallyl thioether compound

The invention discloses a synthesis method of an alpha-acyl homoallyl thioether compound. A series of alpha-acyl homoallyl thioether compounds with application value are finally synthesized by adopting a three-component and one-pot method, taking an alpha-bromoacetophenone compound, a thiol compound and an allyl bromide compound as reactants, taking inorganic salt as an additive, taking an ultra-dry or anhydrous inorganic solvent as a solvent and reacting at the temperature of 60 DEG C to 130 DEG C. The synthesis method disclosed by the invention has the beneficial effects that a series of the homoallyl thioether compounds with the potential application value are synthesized in high yield, and the utilization of a transition metal catalyst and a diazo compound can also be avoided; meanwhile, additives including strong acid, strong alkali and the like are not needed in a reaction process, and the protection of inert gas is not needed; the after treatment of reaction is simple.

Synthesis of Functionalized β-Keto Arylthioethers by the Aryne Induced [2,3] Stevens Rearrangement of Allylthioethers

A mild and transition-metal-free synthesis of β-keto arylthioethers has been developed by the aryne triggered [2,3] Stevens rearrangement of allylthioethers. The key sulfur ylide intermediate for the rearrangement was formed by the S-arylation of allylthi

Aryne triggered [2,3]-sigmatropic rearrangement of allyl and propargyl thioethers

An efficient protocol for [2,3]-sigmatropic rearrangement of allyl and propargyl thioethers is reported. The key sulfonium ylide intermediate is in situ formed via S-arylation of arynes. This transition metal-free method allows for ready access to a wide

Stevens rearrangement of thioethers with arynes: A facile access to multi-substituted β-keto thioethers

An effective method for the synthesis of multi-substituted β-keto thioethers via Stevens rearrangement of simple β-keto thioethers with arynes has been developed. In these reactions, successive C-S/C-H/C-C bonds were formed in one pot under mild and transition-metal free conditions to afford multi-substituted β-keto thioethers in moderate to good yields.

Preparation method of poly-substituted beta-ketone sulfide

The invention relates to a preparation method of poly-substituted beta-ketone sulfide compound. The preparation method includes steps of taking aryne compound, thioether compound and fluoride as reaction reagent composition; preparing a series of compound containing a poly-substituted beta-ketone sulfide framework structure under a gentle reaction condition. The reagent for the reaction is easy to prepare, low in price, simple in post treatment, and very high in atom economy. The invention provides a simple, high-efficient, low-price,high-selective and industrialization-applicable technical manner for the compound.

Expanding the horizon of intermolecular trapping of in situ generated α-oxo gold carbenes: Efficient oxidative union of allylic sulfides and terminal alkynes via C-C bond formation

With a new P,S-bidentate phosphine as the ligand to gold(i), the α-oxo gold carbenes generated in situ via gold-catalyzed intermolecular oxidation of terminal alkynes were effectively trapped by various allylic sulfides, resulting in the formation of α-aryl(alkyl)thio-γ,δ- unsaturated ketones upon facile [2,3]sigmatropic rearrangements. This journal is the Partner Organisations 2014.

Generation of Cation Radicals from Allylic Sulfides and Their Reactions with Silyl Enol Ethers by the Use of Cerium(IV) Ammonium Nitrate

Allyl sulfides react with silyl enol ether, siloxy diene and siloxy enyne by the oxidation with cerium(IV) ammonium nitrate to give α-phenylthio-γ,δ-unsaturated ketones through the nucleophilic addition of silyl enol ethers to the sulfur cation radicals and the successive -sigmatropic rearrangement.