64878-08-6

Basic information

• Product Name: 1-phenyl-2-(prop-2-en-1-ylsulfanyl)ethanone
• CAS NO: 64878-08-6
• Molecular Formula: C₁₁H₁₂OS
• Molecular Weight: 192.2774
• Mol File: 64878-08-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 302.8°C at 760 mmHg
• Flash Point: 148.6°C
• Density: 1.07g/cm³
• Vapor Pressure: 0.00097mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: 1-phenyl-2-(prop-2-en-1-ylsulfanyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-2-(prop-2-en-1-ylsulfanyl)ethanone(64878-08-6)
• EPA Substance Registry System: 1-phenyl-2-(prop-2-en-1-ylsulfanyl)ethanone(64878-08-6)

Safety Data

• Hazardous Substances Data: 64878-08-6(Hazardous Substances Data)

Usage

Explanation

Different sources of media describe the Explanation of 64878-08-6 differently. You can refer to the following data:
1. The compound consists of 11 carbon atoms, 12 hydrogen atoms, 1 oxygen atom, and 1 sulfur atom in a single molecule.
2. The compound appears as a colorless or slightly pale yellow liquid in its pure form.
3. 1-phenyl-2-(prop-2-en-1-ylsulfanyl)ethanone has a pleasant, fruity smell.
4. The compound is also referred to as allyl phenyl ketone in the scientific community and industry.
5. This chemical is widely used in the synthesis of other organic compounds and as a flavoring agent in food products.
6. 1-phenyl-2-(prop-2-en-1-ylsulfanyl)ethanone can cause irritation when it comes into contact with the skin, eyes, or is inhaled.
7. The compound may pose risks to both the environment and human health, so proper safety measures should be taken.
8. To minimize the risks associated with 1-phenyl-2-(prop-2-en-1-ylsulfanyl)ethanone, it is important to handle the compound with care and follow appropriate safety precautions for storage and disposal.

Physical appearance

Colorless to pale yellow liquid

Odor

Fruity

Uses

Synthesis of various organic compounds, flavoring agent in the food industry

Potential irritant effects

Skin, eyes, respiratory system

Environmental and health risks

Yes

Safety precautions

Handle with care, follow proper storage guidelines

Upstream product

• 532-27-4 1-chloroacetophenone 
• 98-88-4 benzoyl chloride 
• 108-86-1 bromobenzene 
• 106-95-6 allyl bromide 
• 49763-80-6 carboethoxymethyl trimethylsilyl sulfide 
• 70-11-1 α-bromoacetophenone 
• 885517-60-2 2-acetyl-3,3-bis-allylsulfanyl-N-o-tolyl-acrylamide 
• 7570-85-6 trans-2,3-epoxy-1,3-diphenyl-1-propanone 
• 16717-64-9 1-azidostyrene 
• 870-23-5 prop-2-ene-1-thiol 
• 96989-38-7 N-methyl-N-<(2-propenylthio)methylene>methanaminium bromide 
• 87234-43-3 2-propenyl ethaneimidothiolate hydrobromide 
• 22651-09-8 N-methyl-N-<<(2-oxo-2-phenylethyl)thio>methylene>methanaminium bromide 

Downstream Products

• 105621-13-4 2-phenyl-3-(phenylthio)furan 
• 174153-62-9 2-phenyl-3-(phenylthio)-1H-pyrrole 
• 15150-84-2 3-phenylpyridazine 
• 135277-65-5 1-phenyl-2-(phenylthio)pent-4-en-1-one 
• 80028-57-5 2‐ethenyl‐4H‐1,3‐dithiine 
• 98-86-2 acetophenone 
• 72731-11-4 α-(methylthio)-α-allylacetophenone 

Relevant articles and documents

Thiol-free chemoenzymatic synthesis of β-ketosulfides

A preparation of β-ketosulfides avoiding the use of thiols is described. The combination of a multicomponent reaction and a lipase-catalysed hydrolysis has been developed in order to obtain high chemical diversity employing a single sulfur donor. This methodology for the selective synthesis of a set of β-ketosulfides is performed under mild conditions and can be set up in one-pot two-step and on a gram-scale.

Synthesis of Functionalized β-Keto Arylthioethers by the Aryne Induced [2,3] Stevens Rearrangement of Allylthioethers

A mild and transition-metal-free synthesis of β-keto arylthioethers has been developed by the aryne triggered [2,3] Stevens rearrangement of allylthioethers. The key sulfur ylide intermediate for the rearrangement was formed by the S-arylation of allylthi

1,4 -S- to O-silyl migration: Multicomponent synthesis of α-thioketones through chemoselective transformation of esters to ketones with organolithium reagents

A [1,4]-S- to O-silyl migration has been exploited to chemoselectively transform esters into ketones by using organolithium reagents, allowing multicomponent synthesis of α-thioketones. Mechanistic studies reveal that this migration proceeds in an intramolecular manner and is more favorable than the corresponding [1,5]-S- to O- and [1,3]-C- to O-silyl migrations. The resulting α-thioketones are valuable building blocks for the synthesis of cyclic or multifunctionalized organosulfur compounds. Productive move: A [1,4]-S- to O-silyl migration has been exploited to chemoselectively transform esters into ketones by using organolithium reagents, allowing the multicomponent synthesis of α-thioketones (see scheme, TMEDA = tetramethylethylenediamine). Mechanistic studies revealed that this migration proceeds in an intramolecular manner and is more favorable than the corresponding [1,5]-S- to O- and [1,3]-C- to O-silyl migrations. The resulting α-thioketones are valuable building blocks for the synthesis of cyclic or multifunctionalized organosulfur compounds.