1352807-16-9Relevant academic research and scientific papers
Study and application of noncatalyzed photoinduced conjugation of azides and cycloocta-1,2,3-selenadiazoles
Jedináková,?ebej,Slanina,Klán,Hlavá?
, p. 4792 - 4795 (2016)
The non-catalyzed cycloaddition of eight structurally different azides with cyclooctyne generated in situ by the photolysis of cycloocta-1,2,3-selenadiazole gives 1,2,3-triazole derivatives as the main products. The application of this reaction was demonstrated by the photoconjugation reaction of cycloocta-1,2,3-selenadiazole with an avidin-modified biotin complex to introduce a new strategy in the non-catalyzed synthesis of bioconjugates.
Organocatalytic synthesis of 1,2,3-triazoles from unactivated ketones and arylazides
Belkheira, Mokhtaria,El Abed, Douniazad,Pons, Jean-Marc,Bressy, Cyril
supporting information; experimental part, p. 12917 - 12921 (2011/12/04)
Organo-click reaction: A new and complementary method to Huisgen's metal-catalyzed triazole synthesis is described using unactivated ketones and arylazides as the substrates and proline as an organocatalyst. Dramatic acceleration was observed for this reaction using microwave activation and high regio- and chemoselectivities were obtained for a wide range of ketones and arylazides (see scheme). Copyright
