1352874-36-2

Upstream product

• 75-36-5 acetyl chloride 
• 948592-80-1 4‐methyl‐2‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)aniline 
• 103-89-9 4-Methylacetanilide 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1352874-37-3 N-[4'-(2-amino-7-methyl-benzoimidazol-1-yl)-5-methyl-biphenyl-2-yl]-acetamide 
• 1352873-39-2 N-[4'-(3-benzyl-2-imino-7-methyl-2,3-dihydro-benzoimidazol-1-yl)-5-methyl-biphenyl-2-yl]-acetamide trifluoroacetic acid 

Relevant academic research and scientific papers

Palladium-catalyzed monoselective C-H borylation of acetanilides under acidic conditions

A practical Pd-catalyzed reaction was developed to achieve C-H activation/C-B cross-coupling of acetanilides under acidic conditions. The new reaction shows a good functional group tolerance and an exclusive mono-selectivity. This C-H borylation method ma

BIPHENYL SUBSTITUTED 1,3-DIHYDRO-BENZOIMIDAZOL-2-YLIDENEAMINE DERIVATIVES

The invention relates to new derivatives of formula (I), wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions comprising such derivatives; such derivatives as a medicament; such derivatives for the treatment of one or more IGF-1R mediated disorders or diseases