135292-58-9Relevant academic research and scientific papers
Synthesis and evaluation of two new inhibitors of EPSP synthase
Pansegrau, Paul D.,Anderson, Karen S.,Widlanski, Theodore,Ream, Joel E.,Douglas Sammons,Sikorski, James A.,Knowles, Jeremy R.
, p. 2589 - 2592 (1991)
The enzyme EPSP synthase, EPSPS, (EC 2.5.1.19) catalyzes an unusual transfer reaction of the enolpyruvoyl moiety from phosphoenol pyruvate (2, PEP) regiospecifically to the 5-OH of shikimate 3-phosphate (1, S3P) to form 5-enol-pyruvoylshikimate 3-phosphate (3, EPSP). Two new inhibitors, (4, and 5) were prepared to probe the S3P binding site.
