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3-Benzyl-3-azabicyclo[3.1.1]heptan-2-one is a bicyclic ketone compound featuring a benzyl group attached to one of the carbon atoms in the bicyclic structure. It is a derivative of azabicyclo[3.1.1]heptane, characterized by a seven-membered ring with a nitrogen atom. This unique structure endows it with valuable properties, making it a significant intermediate in organic synthesis and medicinal chemistry for the development of pharmaceuticals and bioactive compounds. Its intriguing pharmacological properties also position it as a candidate for drug discovery and development.

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  • 1352925-73-5 Structure
  • Basic information

    1. Product Name: 3-benzyl-3-azabicyclo[3.1.1]heptan-2-one
    2. Synonyms: 3-benzyl-3-azabicyclo[3.1.1]heptan-2-one
    3. CAS NO:1352925-73-5
    4. Molecular Formula: C13H15NO
    5. Molecular Weight: 201.2643
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1352925-73-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-benzyl-3-azabicyclo[3.1.1]heptan-2-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-benzyl-3-azabicyclo[3.1.1]heptan-2-one(1352925-73-5)
    11. EPA Substance Registry System: 3-benzyl-3-azabicyclo[3.1.1]heptan-2-one(1352925-73-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1352925-73-5(Hazardous Substances Data)

1352925-73-5 Usage

Uses

Used in Pharmaceutical and Bioactive Compounds Synthesis:
3-Benzyl-3-azabicyclo[3.1.1]heptan-2-one serves as a key building block in the synthesis of various pharmaceuticals and bioactive compounds. Its distinctive structure allows for the creation of a wide range of molecules with potential therapeutic applications.
Used in Drug Discovery and Development:
Due to its pharmacological properties, 3-benzyl-3-azabicyclo[3.1.1]heptan-2-one is utilized in drug discovery and development processes. Researchers investigate its potential applications in treating various diseases and conditions, leveraging its unique chemical features to design new therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, 3-benzyl-3-azabicyclo[3.1.1]heptan-2-one is employed as an intermediate for constructing complex organic molecules. Its versatility in forming different chemical bonds and its stability contribute to its utility in creating a diverse array of organic compounds.
Used in Medicinal Chemistry:
3-Benzyl-3-azabicyclo[3.1.1]heptan-2-one is also used in medicinal chemistry for the design and synthesis of new drugs. Its structural features make it a valuable component in the development of molecules with specific biological activities, potentially leading to the creation of novel therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 1352925-73-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,2,9,2 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1352925-73:
(9*1)+(8*3)+(7*5)+(6*2)+(5*9)+(4*2)+(3*5)+(2*7)+(1*3)=165
165 % 10 = 5
So 1352925-73-5 is a valid CAS Registry Number.

1352925-73-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-benzyl-3-azabicyclo[3.1.1]heptan-4-one

1.2 Other means of identification

Product number -
Other names 3-BENZYL-3-AZABICYCLO[3.1.1]HEPTAN-2-ONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1352925-73-5 SDS

1352925-73-5Relevant articles and documents

ARYL, HETEROARY, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS

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Page/Page column 453; 455, (2018/09/21)

Complement Factor D inhibitors, pharmaceutical compositions, and uses thereof, as well as processes for their manufacture are provided. The compounds provided include Formula I, Formula II, Formula III, Formula IV, and Formula V, or a pharmaceutically acceptable salt, prodrug, isotopic analog, N-oxide, or isolated isomer thereof, optionally in a pharmaceutically acceptable composition. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade.

ANGIOTENSIN-(1-7) ANALOGS AND METHODS RELATING THERETO

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Paragraph 00143; 0147, (2017/07/06)

Angiotensin (1-7) analogs are provided. The analogs contain one or more substitutions with non-natural amino acid cis-3-(aminomethyl)cyclobutanecarboxylic acid (ACCA). Also provided are methods of making such analogs and methods for using such analogs as

Synthesis of a conformationally constrained δ-amino acid building block

O'Reilly, Elaine,Pes, Lara,Ortin, Yannick,Mueller-Bunz, Helge,Paradisi, Francesca

, p. 511 - 518 (2013/07/27)

Conformationally restricted amino acids are important components in peptidomimetics and drug design. Herein, we describe the synthesis of a novel, non-proteinogenic constrained delta amino acid containing a cyclobutane ring, cis-3(aminomethyl)cyclobutane

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