1352942-41-6

Basic information

• Product Name: 1,2-dimethyl-5-(L-phenylalanyl)-amino benzimidazole
• Synonyms: 1,2-dimethyl-5-(L-phenylalanyl)-amino benzimidazole
• CAS NO: 1352942-41-6
• Molecular Weight: 308.383
• Mol File: 1352942-41-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-dimethyl-5-(L-phenylalanyl)-amino benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dimethyl-5-(L-phenylalanyl)-amino benzimidazole(1352942-41-6)
• EPA Substance Registry System: 1,2-dimethyl-5-(L-phenylalanyl)-amino benzimidazole(1352942-41-6)

Safety Data

• Hazardous Substances Data: 1352942-41-6(Hazardous Substances Data)

Upstream product

• 5123-55-7 Nα-phthaloyl-L-phenylalanine 
• 3527-19-3 1,2-dimethyl-1H-benzo[d]imidazole-5-amine 
• 32150-91-7 phthaloyl-L-phenylalanyl chloride 
• 63-91-2 L-phenylalanine 
• 49819-79-6 1,2-dimethyl-5-nitro-1H-benzimidazole 
• 1352942-35-8 1,2-dimethyl-5-(phthaloyl-L-phenylalanyl)-aminobenzimidazole 

Relevant articles and documents

New antibacterial peptide analogs of 5-Aminobenzimidazoles

Three new peptide analogs 5a-c were obtained through coupling of 5-Amino benzimidazoles 2a-c with L-phenylalanine. For the purpose α-amino group was blocked with phthalic anhydride and activation of α-carboxy group of phenylalanine was carried out by preparing phthaloyl-L-phenylalanyl chloride 4. After developing a successful peptide linkage, the phthaloyl group was removed by treating 5a-c with hydrazine hydrate to get free peptides 6a-c, purified through a column of Amberlite (IR-4B). All of these compounds 2a-c and 5,6a-c have been characterized on the basis of their IR, 1H NMR and EIMS analyses. Antibacterial activity of these compounds is also been reported.